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[一例非库欣样库欣综合征病例]

[A case of non-Cushingoid Cushing's syndrome].

作者信息

Yushita Y, Haraguchi T, Sakai H, Suzu H, Kanetake H, Saito Y

机构信息

Department of Urology, Nagasaki University School of Medicine.

出版信息

Hinyokika Kiyo. 1990 Dec;36(12):1429-33.

PMID:1963757
Abstract

A 42-year-old female was admitted to our hospital with a chief complaint of hypertension. Endocrinologically, the plasma cortisol level was increased, but its diurnal rhythm had disappeared and the plasma cortisol level was not suppressed by dexamethasone loading at 2 mg or 8 mg. The plasma ACTH level was low. Computerized tomographic scan, echography and adrenocortical scintigraphy showed an adrenocortical tumor on the right adrenal gland. Physical examination did not reveal typical Cushingoid symptoms such as moon face, central obesity and violaceous striae. Thus we diagnosed this case as non-Cushingoid Cushing's syndrome and performed right adrenalectomy. Histological examination showed adreno-cortical adenoma without malignancy.

摘要

一名42岁女性因高血压主诉入院。在内分泌方面,血浆皮质醇水平升高,但其昼夜节律消失,且2毫克或8毫克地塞米松负荷试验后血浆皮质醇水平未被抑制。血浆促肾上腺皮质激素(ACTH)水平较低。计算机断层扫描、超声检查和肾上腺皮质闪烁显像显示右肾上腺有一个肾上腺皮质肿瘤。体格检查未发现典型的库欣样症状,如满月脸、向心性肥胖和紫纹。因此,我们将该病例诊断为非典型库欣综合征,并进行了右肾上腺切除术。组织学检查显示为无恶性的肾上腺皮质腺瘤。

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