Kim Seong Hyun, Kim Ki Hwan, Kim Dong Soo
Department of Pediatrics, Severance Childrens Hospital, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Korea.
Indian Pediatr. 2009 Jul;46(7):585-90.
We compared the clinical, laboratory and diagnostic features of Kawasaki disease (KD) in children <6 mo and >5 y of age to those in the more typical age range at diagnosis (6 mo-5 y of age).
Retrospective analysis.
Severeance Children Hospital attached to a Medical School, Korea.
All children with a discharge diagnosis of KD at Severance Childrens Hospital (2006-2007) were retrospectively reviewed and grouped according to age at presentation in 3 groups: <6 mo, 6 mo-5 y and >5 years. Clinical, hematological, and biochemical features and involvement of coronary artery and proportion of Classic vs. Incomplete KD were compared between the 3 groups.
A total of 185 children were identified. Complete KD was found in 63 (34%) children and Incomplete KD in 122 (66%). There was 22(12%) children below 6 months of age, 131 (71%) between 6 months to 5 years) and 32 (17%) above 5 years of age. Clinical, hematological and biochemical features were comparable between the three age groups. Overall, coronary artery lesions occurred in 9% children without any preference for age. The proportion of Classical vs. Incomplete KD was also similar in the three age categories.
The clinical and laboratory phenotype of KD does not vary significantly with age.
我们比较了6个月以下和5岁以上儿童川崎病（KD）的临床、实验室及诊断特征与诊断时更典型年龄范围（6个月至5岁）儿童的这些特征。
回顾性分析。
韩国一所医学院附属的Severance儿童医院。
对Severance儿童医院（2006 - 2007年）所有出院诊断为KD的儿童进行回顾性研究，并根据就诊时的年龄分为3组：<6个月、6个月至5岁和>5岁。比较3组之间的临床、血液学和生化特征、冠状动脉受累情况以及典型KD与非典型KD的比例。
共确定了185名儿童。63名（34%）儿童为典型KD，122名（66%）为非典型KD。6个月以下儿童有22名（12%），6个月至5岁儿童有131名（71%），5岁以上儿童有32名（17%）。三个年龄组的临床、血液学和生化特征具有可比性。总体而言，9%的儿童出现冠状动脉病变，且无年龄偏好。三个年龄组中典型KD与非典型KD的比例也相似。
KD的临床和实验室表型不会随年龄显著变化。
