慢性子宫内膜炎的病理诊断与临床发现的关联

Association of pathologic diagnoses with clinical findings in chronic endometritis.

作者信息

Pitsos Miltiadis, Skurnick Joan, Heller Debra

机构信息

Department of Obstetrics and Gynecology and Women's Health, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey, USA.

出版信息

J Reprod Med. 2009 Jun;54(6):373-7.

PMID:19639927

Abstract

OBJECTIVE

To investigate the association of chronic endometritis (CE) with abnormal uterine bleeding, chronic pelvic pain, human immunodeficiency virus (HIV) infection, genital tract infection and salpingitis.

STUDY DESIGN

In this retrospective study, specimens obtained from endometrial biopsy, dilatation and curettage or hysterectomy were identified. A total of 123 patients with CE and 177 without CE who were used as controls were included in the study.

RESULTS

The patients with CE were younger than controls (p = 0.0001) and were more likely to be premenopausal (p = 0.0004). There was no association of CE with body mass index (p = 0.82), pelvic pain (p = 0.88) or abnormal uterine bleeding (p = 0.80). None of the specimens with CE had atrophic endometrium (p = 0.0018). CE was significantly associated with history of genital tract infection (p = 0.0032), HIV infection (p = 0.0018) and salpingitis (p = 0.0007).

CONCLUSION

There was significant association of CE with historical factors, but not with symptomatology.

摘要

目的

探讨慢性子宫内膜炎（CE）与异常子宫出血、慢性盆腔疼痛、人类免疫缺陷病毒（HIV）感染、生殖道感染及输卵管炎之间的关联。

研究设计

在这项回顾性研究中，对取自子宫内膜活检、刮宫术或子宫切除术的标本进行鉴定。该研究共纳入123例患有CE的患者和177例未患CE的患者作为对照。

结果

患有CE的患者比对照组更年轻（p = 0.0001），且更可能处于绝经前（p = 0.0004）。CE与体重指数（p = 0.82）、盆腔疼痛（p = 0.88）或异常子宫出血（p = 0.80）无关联。患有CE的标本中均无萎缩性子宫内膜（p = 0.0018）。CE与生殖道感染史（p = 0.0032）、HIV感染（p = 0.0018）及输卵管炎（p = 0.0007）显著相关。