多个红细胞在毛细血管中的变形行为。
The deformation behavior of multiple red blood cells in a capillary vessel.
作者信息
Gong Xiaobo, Sugiyama Kazuyasu, Takagi Shu, Matsumoto Yoichiro
机构信息
Organ and Body Scale Team, Computational Science Research Program, RIKEN, 2-1, Hirosawa, Wako, Saitama 351-0198, Japan.
出版信息
J Biomech Eng. 2009 Jul;131(7):074504. doi: 10.1115/1.3127255.
The deformation of multiple red blood cells in a capillary flow was studied numerically. The immersed boundary method was used for the fluid red blood cells interaction. The membrane of the red blood cell was modeled as a hyperelastic thin shell. The numerical results show that the apparent viscosity in the capillary flow is more sensitive to the change of shear coefficient of the membrane than the bending coefficient and surface dilation coefficient, and the increase in the shear coefficient results in an increase in the pressure drop in the blood flow in capillary vessels in order to sustain the same flux rate of red blood cells.
对毛细血管流动中多个红细胞的变形进行了数值研究。采用浸入边界法处理流体与红细胞的相互作用。红细胞膜被建模为超弹性薄壳。数值结果表明，毛细血管流动中的表观粘度对膜的剪切系数变化比对弯曲系数和表面膨胀系数变化更敏感，并且剪切系数的增加会导致毛细血管中血流压降增加，以维持相同的红细胞通量率。
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