Badar Farhana, Sattar Ambreen, Meerza Fouzia, Irfan Noureen, Siddiqui Neelam
Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore, Pakistan.
Asian Pac J Cancer Prev. 2009 Jul-Sep;10(3):449-52.
Men have greater incidence and mortality rates than women for bladder cancer. Most bladder cancers are transitional cell carcinomas.
To determine the epidemiologic features of urinary bladder cancer cases presenting at a cancer hospital, from Dec. 1994 through Dec. 2004.
Six-hundred and seven medical records were evaluated retrospectively at the Shaukat Khanum Memorial Cancer Hospital. Gender, age, histologic types, grade, stage, symptoms, risk factors, and patient follow-up were studied. Staging was done through the American Joint Commission on Cancer's criteria. Class of Case was established using the Facility Oncology Registry Data Standards, 2004.
Mean age: 55.5 years; men: 83%. Transitional cell- in 86%, squamous cell- in 4%, adeno- in 3%, and undifferentiated carcinoma in 7% of the cases. Stage: II in 18.3%, I in 17.3%, III in 14.2%, IV in 26%, 0 in 6.3%, and not evaluable in 17.8% of the cases. Grades: G3 in 37.9%, G2 in 25.2%, G1 in 9.7%, G4 in 2.8%, and undetermined in 24.4% of the subjects. Commonest presenting symptom: hematuria in 54.7% men and 52.9% women; risk factor: positive smoking history in nearly 35% males and 2% females. Average interval between diagnosis and last contact: 26.5 months; for analytic cases, 34.9 months.
Urinary bladder cancer was seen primarily in males; transitional cell type was dominant. The majority of the patients were symptomatic; smoking history was recorded mostly in men. Further, improving in staging could be useful in addressing the concerns about data reproducibility over time and use for surveillance purposes.
男性膀胱癌的发病率和死亡率高于女性。大多数膀胱癌为移行细胞癌。
确定1994年12月至2004年12月在一家癌症医院就诊的膀胱癌病例的流行病学特征。
对沙卡特汗姆纪念癌症医院的607份病历进行回顾性评估。研究了性别、年龄、组织学类型、分级、分期、症状、危险因素及患者随访情况。分期依据美国癌症联合委员会的标准进行。病例分类按照2004年设施肿瘤登记数据标准确定。
平均年龄：55.5岁；男性占83%。病例中移行细胞癌占86%，鳞状细胞癌占4%，腺癌占3%，未分化癌占7%。分期：II期占18.3%，I期占17.3%，III期占14.2%，IV期占26%，0期占6.3%，无法评估占17.8%。分级：G3占37.9%，G2占25.2%，G1占9.7%，G4占2.8%，未确定占24.4%。最常见的症状：男性血尿占54.7%，女性血尿占52.9%；危险因素：近35%的男性和2%的女性有吸烟史阳性。诊断至最后一次联系的平均间隔时间：26.5个月；分析病例为34.9个月。
膀胱癌主要见于男性；移行细胞类型占主导。大多数患者有症状；吸烟史大多记录于男性。此外，改进分期有助于解决随着时间推移数据再现性问题以及用于监测目的。
