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[影像引导放射治疗在前列腺癌中的应用(Varian公司的OBI-CBCT、BrainLAB公司的ExacTrac和TomoTherapy公司的MVCT)]

[Use of IGRT for prostate cancers (OBI-CBCT Varian, ExacTrac BrainLAB and MVCT TomoTherapy)].

作者信息

Delpon G, Llagostera C, Le Blanc M, Rio E, Supiot S, Mahé M-A, Lisbona A

机构信息

Service de physique médicale, centre René-Gauducheau, CLCC Nantes Atlantique, 44805 Nantes Saint-Herblain cedex, France.

出版信息

Cancer Radiother. 2009 Sep;13(5):399-407. doi: 10.1016/j.canrad.2009.06.001. Epub 2009 Jul 28.

Abstract

INTRODUCTION

The aim of this work was to report the experience of image-guided radiotherapy at the CLCC Nantes-Atlantique using three repositioning imaging devices, the ExacTrac (BrainLAB), the OBI-CBCT (Varian) and the MVCT (Tomotherapy Inc), in the case of prostate external radiotherapy.

MATERIAL AND METHODS

For each linac and its imaging device, a treatment plan was described. Moreover, studies concerning calculated shifts after imaging sessions were achieved. Using ExacTrac, for eight patients, a study compared daily shifts based on bony anatomy or on implanted markers. Considering mean values of displacements over a course of radiotherapy, dosimetric impact was evaluated. With the OBI-CBCT, two imaging modalities were used, kV-kV (0 degrees and 270 degrees ) and CBCT. Up to now, whatever the images, displacements were calculated using the bony anatomy. For both modalities and for 26 patients, shifts were compared. Since the beginning of the Tomotherapy HiArt use, MVCT was performed for each session of each patient. For 12 patients, mean displacements were calculated after five fractions. Then the deviations to those values were calculated. This was done to show the relevance of daily MVCT.

RESULTS AND CONCLUSION

This work allows us to report the use of three repositioning imaging devices in the radiotherapy department. At least they provide an efficient positioning tool. And they let us see the future radiotherapy which would probably be the dose-guided radiotherapy.

摘要

引言

本研究旨在报告在南特-大西洋癌症中心(CLCC)使用三种重新定位成像设备(ExacTrac(BrainLAB公司)、OBI-CBCT(瓦里安公司)和MVCT(拓能公司))进行前列腺外照射放疗的经验。

材料与方法

针对每个直线加速器及其成像设备,描述了一个治疗计划。此外,还进行了关于成像后计算位移的研究。使用ExacTrac,对8名患者进行了一项研究,比较了基于骨骼解剖结构或植入标记物的每日位移。根据放疗过程中的位移平均值,评估剂量学影响。对于OBI-CBCT,使用了两种成像模式,kV-kV(0度和270度)和CBCT。到目前为止,无论使用何种图像,位移都是根据骨骼解剖结构计算的。对于这两种模式和26名患者,比较了位移。自开始使用螺旋断层放疗系统(Tomotherapy HiArt)以来,对每位患者的每次治疗都进行了MVCT检查。对于12名患者,在五个分次后计算平均位移。然后计算与这些值的偏差。这样做是为了显示每日MVCT的相关性。

结果与结论

本研究使我们能够报告放疗科使用三种重新定位成像设备的情况。至少它们提供了一种有效的定位工具。并且让我们看到了未来可能是剂量引导放疗的放疗模式。

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