体外循环冠状动脉手术中镁术前治疗对心律失常和心肌缺血的影响。
Effects of preoperative magnesium therapy on arrhythmias and myocardial ischemia during off-pump coronary surgery.
机构信息
Department of Cardiovascular Surgery, Osmangazi University Medical School and Research Hospital, Eskişehir, Turkey.
出版信息
Ann Thorac Med. 2009 Jul;4(3):137-9. doi: 10.4103/1817-1737.53355.
BACKGROUND
Heart manipulation during off-pump coronary artery bypass surgery may cause hemodynamic instability, and temporary coronary arterial occlusion may lead to myocardial ischemia. To reduce this, perioperative β-blocking agents or calcium antagonists can be administrated. The effects of perioperative administration of magnesium on myocardial function were studied in patients undergoing coronary artery bypass grafting.
OBJECTIVE
The aim of the study was to evaluate the effects of preoperative magnesium administration on perioperative hemodynamia, ventricular arrhythmias and myocardial protection.
MATERIALS AND METHODS
We reviewed 2 groups of patients undergoing off-pump coronary artery bypass surgery - 24 patients (control group) that had not received preoperative intravenous infusion of magnesium and 23 patients (treatment group) that had received preoperative intravenous magnesium sulfate.
RESULTS
The results demonstrated that it had reduced the heart rate, changes of ST segments, the need of β-blocking agents and the use of intra-operative intra-aortic balloon pump and the inotropic usage.
CONCLUSION
This treatment may provide hemodynamic optimization during off-pump coronary artery bypass.
背景
在非体外循环冠状动脉旁路移植术中进行心脏操作可能会导致血液动力学不稳定，而临时的冠状动脉闭塞可能导致心肌缺血。为了减少这种情况，可以给予围手术期β受体阻滞剂或钙拮抗剂。本研究旨在探讨围手术期给予镁对行冠状动脉旁路移植术患者心肌功能的影响。
目的
研究目的是评估术前给予镁对围手术期血液动力学、室性心律失常和心肌保护的影响。
材料和方法
我们回顾了两组接受非体外循环冠状动脉旁路移植术的患者 - 24 例（对照组）未接受术前静脉内输注镁，23 例（治疗组）接受术前静脉内硫酸镁。
结果
结果表明，它降低了心率、ST 段变化、β受体阻滞剂的需要以及术中主动脉内球囊泵的使用和正性肌力药物的使用。
结论
这种治疗可能为非体外循环冠状动脉旁路提供血液动力学优化。
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