Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013, ROC.
Org Biomol Chem. 2009 Aug 21;7(16):3285-90. doi: 10.1039/b905910e. Epub 2009 Jun 19.
Starting from 4-methylcyclohexanone (7), a concise total synthesis of the pinguisane-type sesquiterpenoid acutifolone A, in racemic form, has been accomplished in 14 steps with an overall yield of 14.5%.
从 4-甲基环己酮(7)出发,以 14.5%的总收率,经过 14 步反应,以非对映异构体形式完成了对平盖醇型倍半萜类化合物刺桐酮 A 的简洁全合成。