Department of Ophthalmology and Catholic Institute for Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Sci Rep. 2019 Jan 22;9(1):315. doi: 10.1038/s41598-018-36668-7.
To evaluate the effectiveness of intrastromal corneal ring segment (ICRS) use in keratoconus after five years. ICRS has been widely used to correct astigmatism and improve visual acuity in keratoconus. Although the short-term outcome is well known to be effective, long-term outcome has rarely been reported. A retrospective chart review was done. A total of 30 eyes diagnosed with keratoconus and treated with INTACS (Addition Technology, Sunnyvale, CA, USA) were included. Visual acuity, refraction, indices of corneal irregularity, and higher-order aberration were evaluated at preoperative, two months, one year, three years, and five years postoperatively. Uncorrected distance visual acuity (UDVA) and spherical and spherical equivalent were improved (p < 0.05) for three years. However, they worsened (p < 0.05) at five years to preoperative values. On the other hand, corrected distance visual acuity (CDVA) was improved for five years (p < 0.05). Topographic keratometry was flattened, and corneal irregularity indices were improved at five years (all p < 0.05). Coma RMS was improved (p < 0.05) continuously for five years. ICRS has advantages in improving CDVA with topographic stabilization and decreasing coma in keratoconus for five years.
评估五年后间质角膜环段（ICRS）在圆锥角膜中的有效性。ICRS 已广泛用于矫正圆锥角膜中的散光并提高视力。尽管其短期效果众所周知是有效的，但很少有长期效果的报道。进行了回顾性图表审查。共纳入 30 只诊断为圆锥角膜并接受 INTACS（Addition Technology，加利福尼亚州桑尼维尔）治疗的眼睛。在术前、术后两个月、一年、三年和五年评估视力、屈光度、角膜不规则指数和高阶像差。未矫正的远视力（UDVA）和球镜和球镜等效值在三年内得到改善（p<0.05）。然而，五年后它们恶化（p<0.05）至术前值。另一方面，五年内矫正远视力（CDVA）得到改善（p<0.05）。五年后角膜地形图变平，角膜不规则指数改善（均 p<0.05）。彗差均方根（RMS）连续五年得到改善（p<0.05）。ICRS 在五年内具有改善 CDVA、稳定地形和降低圆锥角膜彗差的优势。
