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一例复发性多灶性中央巨细胞肉芽肿。

A case of recurrent multifocal central giant cell granulomas.

作者信息

Bilodeau Elizabeth, Chowdhury Khalid, Collins Bobby

机构信息

Department of Diagnostic Sciences, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA.

出版信息

Head Neck Pathol. 2009 Jun;3(2):174-8. doi: 10.1007/s12105-009-0119-0. Epub 2009 Jun 11.

DOI:10.1007/s12105-009-0119-0
PMID:19644538
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2715452/
Abstract

One case of recurrent multifocal central giant cell granulomas (CGCG) is presented. Initially, the lesions presented concurrently in the maxilla and mandible with subsequent recurrence in the mandible. Now, two recurrences are seen in the maxillary sinus and ethmoid region. The literature regarding multifocal CGCG is reviewed.

摘要

本文报告1例复发性多灶性中央巨细胞肉芽肿（CGCG）。最初，病变同时出现在上颌骨和下颌骨，随后下颌骨复发。现在，上颌窦和筛窦区域出现了两次复发。本文对多灶性CGCG的相关文献进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8df7/2811609/d4c84aec6981/12105_2009_119_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8df7/2811609/780cc62b3c8e/12105_2009_119_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8df7/2811609/552648778cf2/12105_2009_119_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8df7/2811609/d4c84aec6981/12105_2009_119_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8df7/2811609/780cc62b3c8e/12105_2009_119_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8df7/2811609/552648778cf2/12105_2009_119_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8df7/2811609/d4c84aec6981/12105_2009_119_Fig3_HTML.jpg

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本文引用的文献

1
Central giant cell tumors of the jaws.颌骨中央巨细胞瘤
J Oral Surg (Chic). 1948 Oct;6(4):324-30.
2
Giant cell tumor of bone express p63.骨巨细胞瘤表达p63。
Mod Pathol. 2008 Apr;21(4):369-75. doi: 10.1038/modpathol.2008.29. Epub 2008 Feb 29.
3
Gene expression profiling identifies p63 as a diagnostic marker for giant cell tumor of the bone.基因表达谱分析确定p63为骨巨细胞瘤的诊断标志物。
免疫组织化学技术对比研究组织蛋白酶D在颌骨外周性和中央性巨细胞肉芽肿中的表达
J Dent (Shiraz). 2016 Jun;17(2):98-104.
4
Nonsyndromic Synchronous Multifocal Central Giant Cell Granulomas of the Maxillofacial Region: Report of a Case.颌面部非综合征性同步多灶性中央巨细胞肉芽肿：1例报告
J Dent (Tehran). 2015 Feb;12(2):157-62.
Mod Pathol. 2008 May;21(5):531-9. doi: 10.1038/modpathol.3801023. Epub 2008 Jan 11.
4
SH3BP2 is rarely mutated in exon 9 in giant cell lesions outside cherubism.在除 cherubism 外的巨细胞病变中，SH3BP2 在第9外显子中很少发生突变。
Clin Orthop Relat Res. 2007 Jun;459:22-7. doi: 10.1097/BLO.0b013e31804b4131.
5
Multiple giant cell lesions of the maxillofacial skeleton.颌面部骨骼的多发性巨细胞病变。
J Oral Maxillofac Surg. 2007 Jun;65(6):1250-3. doi: 10.1016/j.joms.2005.10.046.
6
Giant cell lesions with a Noonan-like phenotype: a case report.具有努南样表型的巨细胞病变：一例报告。
J Contemp Dent Pract. 2007 May 1;8(4):67-73.
7
Peripheral and central giant cell granulomas of the jaws: a demographic study.颌骨外周性和中央性巨细胞肉芽肿：一项人口统计学研究。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jun;103(6):e39-43. doi: 10.1016/j.tripleo.2006.12.022. Epub 2007 Apr 11.
8
Clinically aggressive central giant cell granulomas in two patients with neurofibromatosis 1.两名患有1型神经纤维瘤病的患者出现临床侵袭性中央巨细胞肉芽肿。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Dec;102(6):765-72. doi: 10.1016/j.tripleo.2005.10.038. Epub 2006 Mar 30.
9
Calcitonin therapy in central giant cell granuloma of the jaw: a randomized double-blind placebo-controlled study.
Int J Oral Maxillofac Surg. 2006 Sep;35(9):791-5. doi: 10.1016/j.ijom.2006.03.030. Epub 2006 Jul 10.
10
Limited regression of central giant cell granuloma by interferon alpha after failed calcitonin therapy: a report of 2 cases.降钙素治疗失败后干扰素α使中央巨细胞肉芽肿部分消退：2例报告
Int J Oral Maxillofac Surg. 2006 Sep;35(9):865-9. doi: 10.1016/j.ijom.2006.02.011. Epub 2006 Apr 11.