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头颈部癌的图像引导放射治疗的最新进展。

Recent advances in image-guided radiotherapy for head and neck carcinoma.

机构信息

Department of Radiation Oncology, Rebecca and John Moores Comprehensive Cancer Center, University of California at San Diego, La Jolla, CA 92093-0843, USA.

出版信息

J Oncol. 2009;2009:752135. doi: 10.1155/2009/752135. Epub 2009 Jul 29.

DOI:10.1155/2009/752135
PMID:19644564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2717698/
Abstract

Radiotherapy has a well-established role in the management of head and neck cancers. Over the past decade, a variety of new imaging modalities have been incorporated into the radiotherapy planning and delivery process. These technologies are collectively referred to as image-guided radiotherapy and may lead to significant gains in tumor control and radiation side effect profiles. In the following review, these techniques as they are applied to head and neck cancer patients are described, and clinical studies analyzing their use in target delineation, patient positioning, and adaptive radiotherapy are highlighted. Finally, we conclude with a brief discussion of potential areas of further radiotherapy advancement.

摘要

放射治疗在头颈部癌症的治疗中具有明确的作用。在过去的十年中,各种新的成像方式已经被纳入放射治疗计划和实施过程中。这些技术统称为图像引导放射治疗,可能会显著提高肿瘤控制率和降低放射副作用。在以下综述中,我们将描述这些技术在头颈部癌症患者中的应用,并强调分析其在靶区勾画、患者定位和自适应放射治疗中应用的临床研究。最后,我们简要讨论了放射治疗进一步发展的潜在领域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0e/2717698/deeebb834bbf/JO2009-752135.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0e/2717698/deeebb834bbf/JO2009-752135.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0e/2717698/deeebb834bbf/JO2009-752135.001.jpg

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本文引用的文献

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Initial clinical experience with helical tomotherapy for head and neck cancer.螺旋断层放疗治疗头颈部肿瘤的初步临床经验。
Head Neck. 2009 Dec;31(12):1571-8. doi: 10.1002/hed.21123.
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Targeted gold nanoparticles enable molecular CT imaging of cancer.靶向金纳米颗粒可实现癌症的分子计算机断层扫描成像。
Nano Lett. 2008 Dec;8(12):4593-6. doi: 10.1021/nl8029114.
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Proton therapy for prostate cancer treatment employing online image guidance and an action level threshold.采用在线图像引导和行动水平阈值的前列腺癌质子治疗。
Clinical outcomes of adaptive radiotherapy in head and neck cancers.
头颈部癌自适应放疗的临床结果
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Osteoradionecrosis of the mandible and mastoiditis after radiotherapy for parotid mucoepidermoid carcinoma.腮腺黏液表皮样癌放疗后下颌骨放射性骨坏死及乳突炎
Clin Med Res. 2012 May;10(2):78-82. doi: 10.3121/cmr.2011.1028. Epub 2011 Oct 26.
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