Béress L, Bodendiek I, Forssmann W G, Gresch U, Kallsen B, Lammers T, Ständker L, Thieme F, Bruhn H D
Abteilung für Immunologie, Klinische und Experimentelle Peptidchemie, Medizinische Hochschule Hannover.
Hamostaseologie. 2009 Aug;29(3):291-7.
Comparative investigation concerning gelfiltration as well as haemostaseologic analysis of venoms and venom fractions of some snakes (elapidae and viperidae) have shown that in elapidae an inhibition of coagulation is dominant whilst in viperidae the stimulation of coagulation is of importance. Our investigations produce a basis to select substances for activation of coagulation and substances for inhibition of coagulation. Under pharmacological viewpoints the data may produce information to use snake fractions for anticoagulation or for procoagulant therapy in bleeding tendency.
关于某些蛇（眼镜蛇科和蝰蛇科）毒液及毒液组分的凝胶过滤以及止血学分析的比较研究表明，在眼镜蛇科中，凝血抑制占主导，而在蝰蛇科中，凝血刺激则很重要。我们的研究为选择用于激活凝血的物质和抑制凝血的物质奠定了基础。从药理学角度来看，这些数据可能为在出血倾向中使用蛇毒组分进行抗凝或促凝血治疗提供信息。
