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[活体供肾移植:手术过程]

[Living donor kidney transplant: the surgical procedure].

作者信息

Furian L, Rigotti Paolo

机构信息

SSD Trapianti Rene e Pancreas, Azienda Ospedaliera, Università degli Studi, Padova.

出版信息

G Ital Nefrol. 2009 Jul-Aug;26(4):516-22.

Abstract

The ideal nephrectomy technique for living donors should preserve donor safety and maximize graft quality for the recipient. The laparoscopic technique performs as well as the traditional open technique and has become the procedure of choice in up to 70% of the transplant centers in the US. Since November 2001, 70 living donor kidney transplants have been performed at the Transplant Center of Padua: 42 of the donors underwent laparoscopic left nephrectomy, 28 standard open nephrectomy. Donor and recipient results were analyzed retrospectively. After a mean follow-up of 38+/-26 months (laparoscopic group) and 40+/-27 months (open nephrectomy group) no deaths had occurred among the donors. Only one minor surgical complication was registered (hernia at the port site in a laparoscopic donor). Renal function was optimal in both groups of recipients, without significant differences in the incidence of delayed graft function and acute rejection. Minimally invasive approaches to donor nephrectomy are as safe and effective as the traditional open technique, minimizing postoperative pain and disability, and providing a better cosmetic result.

摘要

对于活体供体而言,理想的肾切除术应确保供体安全,并使受体的移植物质量最大化。腹腔镜技术与传统开放技术的效果相当,在美国多达70%的移植中心,它已成为首选术式。自2001年11月以来,帕多瓦移植中心已进行了70例活体供肾移植手术:42例供体接受了腹腔镜左肾切除术,28例接受了标准开放肾切除术。对供体和受体的结果进行了回顾性分析。在平均随访38±26个月(腹腔镜组)和40±27个月(开放肾切除术组)后,供体中无死亡病例。仅记录到1例轻微手术并发症(1例腹腔镜供体的穿刺孔处发生疝)。两组受体的肾功能均最佳,移植肾功能延迟和急性排斥反应的发生率无显著差异。供体肾切除术的微创方法与传统开放技术一样安全有效,可将术后疼痛和残疾降至最低,并提供更好的美容效果。

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