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[妇科腹腔镜手术期间血液中脂质过氧化速率和抗氧化防御的评估]

[Evaluation of the rate of lipid peroxidation and antioxidant defense in blood during gynecological laparoscopic operations].

作者信息

Poliakova V A, Vinokurova E A, Suplotov S N, Zhuravleva T D, Karpova I A, Iaskevich N N, Malkhazova M T, Karmatskikh T N

出版信息

Klin Lab Diagn. 2009 Jun(6):37-9.

PMID:19645117
Abstract

The impact of gynecological operations on the rate of lipid peroxidation (LPO) and erythrocytic antioxidant defense (EAOD) was studied in women with uterine myoma. The higher rate of LPO and the decreased level of vitamin E were preoperatively found. A further increase in LPO activity and a reduction in vitamin E concentrations were observed 1-4 days after surgery. Recovery of the study parameters was seen on days 5-7 postoperatively. The enzyme glutathione-S-transferase was ascertained to play a pivotal role in the EAOD system.

摘要

研究了子宫肌瘤女性患者妇科手术对脂质过氧化(LPO)率和红细胞抗氧化防御(EAOD)的影响。术前发现LPO率较高且维生素E水平降低。术后1 - 4天观察到LPO活性进一步升高,维生素E浓度降低。术后5 - 7天观察到研究参数恢复。已确定谷胱甘肽 - S - 转移酶在EAOD系统中起关键作用。

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