Holzhauer M, Roest H I J, de Jong M G, Vos J H
Tijdschr Diergeneeskd. 2009 Jul 1;134(13):564-70.
Botulism affects about 20 dairy herds a year in the Netherlands. This article describes the dramatic outcome of botulism in a dairy herd. The main clinical symptoms in this herd were increased lying down, slight ataxia of the hind legs, and a high mortality (98%). The diagnosis is difficult to establish in adult cattle, and for this reason the clinical and laboratory findings, differential diagnosis, therapy, and preventive measures are discussed. On the basis of this outbreak, previous experience with botulism, and cases described in literature, it is suggested that presence of 'free-range" poultry could contaminate grazing pastures with botulism neurotoxins, causing clinical problems in cattle. If there is an increased risk of contamination of the pasture and/or silage with botulinum neurotoxins, vaccination should be considered to prevent substantial economic and emotional damage.
在荷兰，肉毒中毒每年影响约20个奶牛群。本文描述了一个奶牛群中肉毒中毒的严重后果。该牛群的主要临床症状为躺卧增加、后肢轻度共济失调和高死亡率（98%）。成年牛的诊断很难确定，因此本文讨论了临床和实验室检查结果、鉴别诊断、治疗及预防措施。基于此次疫情、以往肉毒中毒经验以及文献中描述的病例，提示“散养”家禽的存在可能会用肉毒中毒神经毒素污染放牧牧场，从而给牛群带来临床问题。如果牧场和/或青贮饲料被肉毒杆菌神经毒素污染的风险增加，则应考虑进行疫苗接种，以防止造成重大的经济和情感损失。
