芽殖酵母细胞周期调控的数学模型。

Mathematical model of the cell cycle regulation in budding yeasts.

作者信息

Prikrylová D, Bucánek D

机构信息

Institute of Microbiology, Czechoslovak Academy of Sciences, Praha.

出版信息

Biomed Biochim Acta. 1990;49(8-9):733-6.

PMID:1964555

Abstract

A mathematical model of the cell cycle regulation in S. cerevisiae is proposed. The model is based on the assumption of the G1----S phase transition control mediated by two signals. One of them is correlated with the cellular energy level--its messenger could be cAMP; the second one depends on the change of the cellular growth rate (reaching the critical size) and remains hypothetical.

摘要

提出了酿酒酵母细胞周期调控的数学模型。该模型基于由两个信号介导的G1期到S期转变控制的假设。其中一个信号与细胞能量水平相关，其信使可能是环磷酸腺苷（cAMP）；另一个信号取决于细胞生长速率的变化（达到临界大小），目前仍是假设的。