Wagner Judith, Lehnen Nadine, Glasauer Stefan, Strupp Michael, Brandt Thomas
Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Munich, Germany.
Ann N Y Acad Sci. 2009 May;1164:479-81. doi: 10.1111/j.1749-6632.2009.03767.x.
Downbeat nystagmus (DBN) is a common form of acquired involuntary ocular oscillation overriding fixation. Little is known about the natural evolution of DBN in idiopathic cases. Therefore, eye movements were recorded in seven patients with idiopathic DBN by search-coil technique over a course of up to six years. Neither the slow-phase velocity (SPV) nor the dependency of the SPV on gaze position as an indicator of dysfunction of the oculomotor velocity-to-position integrator changed significantly over the time course investigated in this study.
下跳性眼球震颤（DBN）是一种常见的后天性非自主性眼球摆动，可克服注视。对于特发性病例中DBN的自然演变知之甚少。因此，通过搜索线圈技术对7例特发性DBN患者进行了长达6年的眼动记录。在本研究调查的时间过程中，慢相速度（SPV）以及作为眼球运动速度-位置整合器功能障碍指标的SPV对注视位置的依赖性均未发生显著变化。
