Yoshida Hiroshi, Mamada Yasuhiro, Taniai Nobuhiko, Mizuguchi Yoshiaki, Kakinuma Daisuke, Ishikawa Yoshinori, Kanda Tomohiro, Bando Koichi, Akimaru Koho, Tajiri Takashi
Department of Surgery, Nippon Medical School, Tokyo, Japan.
J Gastroenterol Hepatol. 2009 May;24(5):752-6. doi: 10.1111/j.1440-1746.2009.05827.x.
We compared two types of stents in patients who underwent surgery for hepatic hilar malignancies.
Twenty-one patients with hepatic hilar malignancies who underwent hepatectomy were randomly assigned to one of two groups. A 5-Fr silicon drain with an internal lumen and side holes was used for the hepaticojejunostomy in one group (intraluminal stent group), and a 10-Fr silicon drain with channels along the sides was used in the other (channel stent group).
Leakage developed in four patients (36.4%) in the intraluminal stent group versus two (20.0%) in the channel stent group. Cholangitis developed in three patients with leakage (27.3%) in the intraluminal stent group versus no patient in the channel stent group. After operation, the times required for the serum alkaline phosphatase and total bilirubin levels to return to the normal range were significantly shorter in the channel stent group (5.3 +/- 2.9, 3.8 +/- 2.2 days) than in the intraluminal stent group (17.0 +/- 5.8, 9.4 +/- 5.7 days) (P < 0.0001, P = 0.0093).
A 10-Fr silicon drain with channels is superior to a 5-Fr silicon drain with an internal lumen for internal biliary stenting of hepaticojejunostomy in patients with hepatic hilar malignancies.
我们比较了两种类型的支架在肝门部恶性肿瘤手术患者中的应用。
21例行肝切除术的肝门部恶性肿瘤患者被随机分为两组。一组(腔内支架组)在肝空肠吻合术中使用带有内腔和侧孔的5Fr硅胶引流管,另一组(通道支架组)使用带有沿侧面通道的10Fr硅胶引流管。
腔内支架组有4例患者(36.4%)发生渗漏,而通道支架组有2例(20.0%)。腔内支架组有3例渗漏患者(27.3%)发生胆管炎,通道支架组无患者发生。术后,通道支架组血清碱性磷酸酶和总胆红素水平恢复至正常范围所需时间(分别为5.3±2.9天和3.8±2.2天)显著短于腔内支架组(分别为17.0±5.8天和9.4±5.7天)(P<0.0001,P=0.0093)。
对于肝门部恶性肿瘤患者的肝空肠吻合术胆道内支架置入,带有通道的10Fr硅胶引流管优于带有内腔的5Fr硅胶引流管。