Reali L, Zuliani E, Gabutti L, Schönholzer C, Marone Claudio
Department of Maslicalory Disorders and Removable Prosthodontics, Dental School University of Zürich, Bellinzona, Switzerland.
J Clin Pharm Ther. 2009 Jun;34(3):255-60. doi: 10.1111/j.1365-2710.2008.01000.x.
To estimate the prevalence of gingival overgrowth in kidney allograft recipients in southern Switzerland and to determine the factors associated with it. We hypothesized that poor oral hygiene was a risk factor.
We assessed the level of oral hygiene among renal transplant patients and determined whether a good level of information and regular dental checkups in addition to good oral hygiene could prevent gingival hyperplasia. Seventy-six adults who had undergone kidney transplantation were examined. The level of oral hygiene, gender, age, time elapsed from transplantation, medication and dose were recorded.
In general the level of oral hygiene was average. We found a significant association between the severity of gingival overgrowth and the level of oral hygiene. No statistical relationship between gingival hyperplasia and the other recorded variables was detected. Patients on tacrolimus had a tendency to have less gingival hyperplasia. Patient education, along with regular dental checkups and a good level of oral hygiene, should prevent gingival hyperplasia or maintain it at an acceptable level.
Intensive motivation of patients to maintain good oral hygiene is necessary to reduce the incidence of gingival hyperplasia.
评估瑞士南部肾移植受者牙龈增生的患病率，并确定与之相关的因素。我们假设口腔卫生差是一个危险因素。
我们评估了肾移植患者的口腔卫生水平，并确定除良好的口腔卫生外，良好的信息水平和定期的牙科检查是否可以预防牙龈增生。对76名接受肾移植的成年人进行了检查。记录了口腔卫生水平、性别、年龄、移植后的时间、用药情况和剂量。
总体而言，口腔卫生水平一般。我们发现牙龈增生的严重程度与口腔卫生水平之间存在显著关联。未检测到牙龈增生与其他记录变量之间的统计关系。使用他克莫司的患者牙龈增生倾向较小。患者教育以及定期的牙科检查和良好的口腔卫生水平应能预防牙龈增生或将其维持在可接受的水平。
为降低牙龈增生的发生率，有必要大力激励患者保持良好的口腔卫生。
