Grabocka Elda, Bar-Sagi Dafna
Department of Biochemistry, New York University School of Medicine, New York, NY 10016, USA.
Cancer Cell. 2009 Aug 4;16(2):85-6. doi: 10.1016/j.ccr.2009.07.012.
Squamous cell carcinoma (SCC) is the second most common form of nonmelanoma skin cancer. In this issue of Cancer Cell, Ehrenreiter et al. unveil a critical role for the Raf-1/Rok-alpha interaction in the pathogenesis of SCCs, thus paving the way for the development of therapeutic modalities to treat this malignancy.
鳞状细胞癌（SCC）是非黑色素瘤皮肤癌的第二常见形式。在本期《癌细胞》杂志中，埃伦赖特等人揭示了Raf-1/Rok-α相互作用在SCC发病机制中的关键作用，从而为开发治疗这种恶性肿瘤的治疗方法铺平了道路。
