Reddy P J, Bhade S P D, Narayan K K, Narayanan A, Babu D A R, Sharma D N
Radiation Safety Systems Division, Bhabha Atomic Research Centre, Mumbai, India.
Appl Radiat Isot. 2009 Oct;67(10):1945-51. doi: 10.1016/j.apradiso.2009.07.006. Epub 2009 Jul 19.
Different methods such as full spectrum DPM (FSDPM), dual isotope estimation and inclusion methods were studied for the activity quantification of (3)H and (14)C in dual beta labeled samples using liquid scintillation analyzer. A standardized Packard tritiated water was used as tritium source and (14)C activity was standardized by CIEMAT/NIST method and compared with the results obtained by the above three methods. Minimum detectable activity was 2100dpm/l for (3)H and 1200dpm/l for (14)C with a counting time of 300min. The accuracy of the results obtained was found to be within +/-10% for (3)H: (14)C activity ratios 1:1, 1:2, 2:1, 6:1, 9:1, 13:1 and 18:1.
研究了全谱双标记法（FSDPM）、双同位素估算法和加入法等不同方法，使用液体闪烁分析仪对双β标记样品中的³H和¹⁴C进行活度定量。使用标准化的帕卡德氚水作为氚源，¹⁴C活度通过CIEMAT/NIST方法进行标准化，并与上述三种方法获得的结果进行比较。³H的最低可探测活度为2100dpm/l，¹⁴C为1200dpm/l，计数时间为300分钟。对于³H:¹⁴C活度比为1:1、1:2、2:1、6:1、9:1、13:1和18:1的情况，发现所获结果的准确度在±10%以内。
