Bekx M Tracy, Connor Ellen C, Allen David B
Department of Pediatric Endocrinology, American Family Children's Hospital, Madison, Wisconsin, USA.
J Pediatr Adolesc Gynecol. 2010 Feb;23(1):7-10. doi: 10.1016/j.jpag.2009.04.004. Epub 2009 Aug 3.
To characterize patients referred to the adolescent polycystic ovarian syndrome (PCOS) clinic at the American Family Children's Hospital, University of Wisconsin, Madison, Wisconsin.
Chart review of patients seen in the first 33 months for details of initial presentation, age, body mass index (BMI), menstrual pattern, clinical and laboratory features of androgen excess, insulin resistance, and dyslipidemia.
Multidisciplinary clinic for adolescents with PCOS at the American Family Children's Hospital, Madison, Wisconsin.
Adolescent girls with PCOS.
Seventy patients (84% Caucasian) presented with an average age at referral of 16.2 years (range 11-22 y). Eighty four percent had a BMI > the 85(th) percentile and 70% had a BMI > 95(th) percentile. Menstrual pattern was quite varied, with some patients having primary amenorrhea, and over 50% experiencing hirsutism. There were 3 cases of type 2 diabetes, and over half of the patients had elevated fasting insulin levels and low HDL levels.
Polycystic ovarian syndrome is a complex and heterogeneous disorder that requires multidisciplinary expertise. Knowing the unique features of the adolescent with PCOS and metabolic risks should permit earlier intervention with intensive counseling and medical therapy to address current health concerns and prevent future co-morbidities.
对转诊至威斯康星大学麦迪逊分校美国家庭儿童医院青少年多囊卵巢综合征（PCOS）门诊的患者进行特征描述。
回顾前33个月就诊患者的病历，以获取初始表现、年龄、体重指数（BMI）、月经模式、雄激素过多、胰岛素抵抗和血脂异常的临床及实验室特征等详细信息。
威斯康星州麦迪逊市美国家庭儿童医院的青少年PCOS多学科门诊。
患有PCOS的青春期女孩。
70例患者（84%为白种人）转诊时的平均年龄为16.2岁（范围11 - 22岁）。84%的患者BMI超过第85百分位数，70%的患者BMI超过第95百分位数。月经模式差异很大，一些患者有原发性闭经，超过50%的患者有多毛症。有3例2型糖尿病患者，超过一半的患者空腹胰岛素水平升高且高密度脂蛋白水平低。
多囊卵巢综合征是一种复杂的异质性疾病，需要多学科专业知识。了解青春期PCOS患者的独特特征和代谢风险，应有助于通过强化咨询和药物治疗进行早期干预，以解决当前的健康问题并预防未来的合并症。
