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本文引用的文献

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Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome.国际循证指南关于多囊卵巢综合征评估和管理的推荐意见。
Fertil Steril. 2018 Aug;110(3):364-379. doi: 10.1016/j.fertnstert.2018.05.004. Epub 2018 Jul 19.
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Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome.多囊卵巢综合征评估与管理的国际循证指南推荐意见。
Clin Endocrinol (Oxf). 2018 Sep;89(3):251-268. doi: 10.1111/cen.13795. Epub 2018 Jul 19.
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An International Consortium Update: Pathophysiology, Diagnosis, and Treatment of Polycystic Ovarian Syndrome in Adolescence.国际联合会更新:青少年多囊卵巢综合征的病理生理学、诊断和治疗。
Horm Res Paediatr. 2017;88(6):371-395. doi: 10.1159/000479371. Epub 2017 Nov 13.
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Polycystic ovary syndrome throughout a woman's life.女性一生中的多囊卵巢综合征
J Assist Reprod Genet. 2018 Jan;35(1):25-39. doi: 10.1007/s10815-017-1047-7. Epub 2017 Sep 27.
5
Clinical and metabolic characteristics of Turkish adolescents with polycystic ovary syndrome.患有多囊卵巢综合征的土耳其青少年的临床和代谢特征。
J Obstet Gynaecol. 2018 Feb;38(2):236-240. doi: 10.1080/01443615.2017.1345875. Epub 2017 Sep 18.
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High prevalence of moderate and severe depressive and anxiety symptoms in polycystic ovary syndrome: a systematic review and meta-analysis.多囊卵巢综合征中中度和重度抑郁及焦虑症状的高患病率:一项系统评价和荟萃分析。
Hum Reprod. 2017 May 1;32(5):1075-1091. doi: 10.1093/humrep/dex044.
7
Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome.神经内分泌雄激素作用是多囊卵巢综合征发生的关键卵巢外中介因素。
Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):E3334-E3343. doi: 10.1073/pnas.1616467114. Epub 2017 Mar 20.
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The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis.多囊卵巢综合征的患病率及表型特征:一项系统评价与荟萃分析
Hum Reprod. 2016 Dec;31(12):2841-2855. doi: 10.1093/humrep/dew218. Epub 2016 Sep 22.
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The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited.多囊卵巢综合征(PCOS)的发病机制:重新审视PCOS作为功能性卵巢雄激素过多症的假说
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[Prevalence of eating disorders among women with polycystic ovary syndrome].[多囊卵巢综合征女性中饮食失调的患病率]
Psychiatr Hung. 2016;31(2):136-45.

青少年多囊卵巢综合征

Polycystic Ovary Syndrome in Adolescence.

作者信息

Deans Rebecca

机构信息

University of New South Wales, Royal Hospital for Women, Sydney Children's Hospital, Sydney 2031, Australia.

出版信息

Med Sci (Basel). 2019 Oct 2;7(10):101. doi: 10.3390/medsci7100101.

DOI:10.3390/medsci7100101
PMID:31581747
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6835615/
Abstract

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in females, and is characterized by ovulatory dysfunction, hyperandrogenism, and polycystic ovarian morphology based on ultrasound. Controversy surrounds the optimum diagnosis and management in the adolescent population. Many patients with adult PCOS present with pathognomonic symptoms as adolescents, and there is value in early diagnosis due to the associated long-term metabolic and reproductive health sequalae. A definitive diagnosis does not need to be made prior to implementing treatment in this group of young women. The practitioner who has an adolescent presenting with signs and symptoms of PCOS, has a unique opportunity to risk stratify, screen for co-morbidities, and implement early management strategies, many of which are lifestyle modifications, to help prevent long term morbidity associated with this disease.

摘要

多囊卵巢综合征(PCOS)是女性最常见的内分泌疾病之一,其特征是排卵功能障碍、高雄激素血症以及基于超声检查的多囊卵巢形态。青少年人群的最佳诊断和管理存在争议。许多成年多囊卵巢综合征患者在青少年时期就出现了特征性症状,鉴于其相关的长期代谢和生殖健康后果,早期诊断具有重要意义。在这群年轻女性中,无需在实施治疗前做出明确诊断。对于有青少年出现多囊卵巢综合征体征和症状的医生来说,有一个独特的机会进行风险分层、筛查合并症,并实施早期管理策略,其中许多是生活方式的改变,以帮助预防与该疾病相关的长期发病情况。