Deans Rebecca
University of New South Wales, Royal Hospital for Women, Sydney Children's Hospital, Sydney 2031, Australia.
Med Sci (Basel). 2019 Oct 2;7(10):101. doi: 10.3390/medsci7100101.
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in females, and is characterized by ovulatory dysfunction, hyperandrogenism, and polycystic ovarian morphology based on ultrasound. Controversy surrounds the optimum diagnosis and management in the adolescent population. Many patients with adult PCOS present with pathognomonic symptoms as adolescents, and there is value in early diagnosis due to the associated long-term metabolic and reproductive health sequalae. A definitive diagnosis does not need to be made prior to implementing treatment in this group of young women. The practitioner who has an adolescent presenting with signs and symptoms of PCOS, has a unique opportunity to risk stratify, screen for co-morbidities, and implement early management strategies, many of which are lifestyle modifications, to help prevent long term morbidity associated with this disease.
多囊卵巢综合征(PCOS)是女性最常见的内分泌疾病之一,其特征是排卵功能障碍、高雄激素血症以及基于超声检查的多囊卵巢形态。青少年人群的最佳诊断和管理存在争议。许多成年多囊卵巢综合征患者在青少年时期就出现了特征性症状,鉴于其相关的长期代谢和生殖健康后果,早期诊断具有重要意义。在这群年轻女性中,无需在实施治疗前做出明确诊断。对于有青少年出现多囊卵巢综合征体征和症状的医生来说,有一个独特的机会进行风险分层、筛查合并症,并实施早期管理策略,其中许多是生活方式的改变,以帮助预防与该疾病相关的长期发病情况。