Hong L, Levy S M, Warren J J, Broffitt B
Department of Dental Public Health and Behavioral Science, School of Dentistry, University of Missouri- Kansas City, Kansas City, Mo. 64108-2784, USA.
Caries Res. 2009;43(5):345-53. doi: 10.1159/000231571. Epub 2009 Aug 1.
The purpose of this study was to assess the longitudinal relationships between enamel hypoplasia and caries experience of primary second molars. The study sample was 491 subjects who received dental examinations at both age 5 and 9 by the calibrated examiners. Four primary second molars (n = 1,892) were scored for the presence of enamel hypoplasia for each participant. Caries presence and number of decayed and filled surfaces (dfs) were determined at age 5 and 9. The relationships between enamel hypoplasia and caries experience were assessed. Among primary second molars, 3.9% of children and 1.7% of primary second molars had enamel hypoplasia. At age 5, 36.8% of children with hypoplasia had caries, while 16.9% of children without enamel hypoplasia had caries. At age 9, the corresponding numbers were 52.6% for children with hypoplasia and 34.5% for children without hypoplasia, respectively. At the tooth level, for age 5, 28.1% of teeth with hypoplasia had caries (mean dfs = 0.40), and 7.6% of teeth without hypoplasia had caries (mean dfs = 0.11). At age 9, the corresponding numbers were 41.9% (mean dfs = 0.76) for teeth with hypoplasia and 18.3% (mean dfs = 0.34) for teeth without hypoplasia. In multivariable logistic regression analyses, teeth of subjects with enamel hypoplasia had a significantly higher risk for caries at age 5 and 9 after controlling for other risk factors. Enamel hypoplasia appears to be a significant risk factor for caries and should be considered in caries risk assessment.
本研究的目的是评估乳牙第二磨牙釉质发育不全与龋病经历之间的纵向关系。研究样本为491名在5岁和9岁时接受了经过校准的检查人员进行牙科检查的受试者。为每位参与者的四颗乳牙第二磨牙（n = 1892）记录釉质发育不全的情况。在5岁和9岁时确定龋病的存在情况以及龋坏和充填面的数量（dfs）。评估了釉质发育不全与龋病经历之间的关系。在乳牙第二磨牙中，3.9%的儿童和1.7%的乳牙第二磨牙存在釉质发育不全。在5岁时，患有釉质发育不全的儿童中有36.8%患龋，而没有釉质发育不全的儿童中有16.9%患龋。在9岁时，患有釉质发育不全的儿童和没有釉质发育不全的儿童的相应比例分别为52.6%和34.5%。在牙齿层面，5岁时，患有釉质发育不全的牙齿中有28.1%患龋（平均dfs = 0.40），没有釉质发育不全的牙齿中有7.6%患龋（平均dfs = 0.11）。在9岁时，患有釉质发育不全的牙齿和没有釉质发育不全的牙齿的相应比例分别为41.9%（平均dfs = 0.76）和18.3%（平均dfs = 0.34）。在多变量逻辑回归分析中，在控制了其他风险因素后，患有釉质发育不全的受试者的牙齿在5岁和9岁时患龋的风险显著更高。釉质发育不全似乎是龋病的一个重要风险因素，应在龋病风险评估中予以考虑。
