White Bronwyn, Chamberlain Nick
Postgraduate Public Health studies, Centre for Public Health Research-Massey University, Wellington, New Zealand.
N Z Med J. 2009 May 22;122(1295):28-37.
To describe the results of a pilot project of diabetes screening in a high risk general practice population.
Adequacy of follow-up of fasting plasma glucose (FPG) tests and recording of cardiovascular risk scores was analysed, and the prevalence of diabetes and impaired glucose tolerance (IGT) was calculated using WHO diagnostic criteria.
In a registered population of 28,000, 1251 people were screened for diabetes of which 1129 (90.2%) completed the screening pathway. Diabetes was detected in 3.6% (n=24) of Maori and 2.0% (n=9) of non-Maori. There was no statistical difference between uptake to oral glucose tolerance (OGT) for Maori and non-Maori. Eighty percent (n=1002/1251) of people screened for diabetes had a Cardiovascular Risk Assessment (CVRA). This occurred less frequently in Maori (76.6%, 576/752) compared to non-Maori (85.4%, 426/499), p=0.0001.
The consequences of low uptake of OGT ranged from underestimated prevalence estimates to underestimated CVD risk scores. Increased follow-up of raised FPGs is required. Because CVRA uptake was lower in Maori, caution is advised against reliance on CVRA programmes as the sole mechanism to identify Maori with diabetes or IGT. Further investigations into the use of HbA1c as a screening or diagnostic test are recommended for high risk groups.
描述一项针对高风险全科医疗人群的糖尿病筛查试点项目的结果。
分析空腹血糖(FPG)检测的随访充分性以及心血管风险评分的记录情况,并使用世界卫生组织诊断标准计算糖尿病和糖耐量受损(IGT)的患病率。
在28000名登记人口中,1251人接受了糖尿病筛查,其中1129人(90.2%)完成了筛查流程。在毛利人中检测出糖尿病的比例为3.6%(n = 24),非毛利人为2.0%(n = 9)。毛利人和非毛利人接受口服葡萄糖耐量试验(OGT)的比例无统计学差异。接受糖尿病筛查的人群中有80%(n = 1002/1251)进行了心血管风险评估(CVRA)。与非毛利人(85.4%,426/499)相比,毛利人进行CVRA的比例较低(76.6%,576/752),p = 0.0001。
OGT接受率低的后果包括患病率估计值被低估以及心血管疾病风险评分被低估。需要加强对FPG升高情况的随访。由于毛利人对CVRA的接受率较低,建议谨慎对待将CVRA项目作为识别患有糖尿病或IGT的毛利人的唯一机制。建议对高危人群进一步研究使用糖化血红蛋白(HbA1c)作为筛查或诊断测试的情况。