Wan Feng-Guo, Zhang Xue-Lan, Shao Xue-Jun, Xu Jun, Ding Yun-Fang
Clinical Laboratory, Children's Hospital Affiliated to Suzhou University, Suzhou, Jiangsu 215003, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2009 Jul;11(7):529-31.
To investigate the viral pathogens of acute respiratory infection (ARI) in hospitalized children from Suzhou of China.
The nasopharyngeal aspirate samples were obtained from 1,668 hospitalized children with ARI. Common respiratory viruses, including respiratory syncytial virus (RSV), influenza virus A and B, parainfluenza viruses 1, 2 and 3 and adenovirus, were detected using direct immunofluorescence. Human metapneumovirus (hMPV) gene fragments were detected by RT-PCR.
Viral agents were identified in 597 cases (35.8%). RSV was the most frequent (17.6%). RSV infection is more common in children less than 1 year old. A highest detection rate of RSV was found during winter and spring. hMPV was detected in 10.6% of the cases, with a peak detection rate between March and May. Single viral infection was found in 561 cases (33.6%) and mixed viral infection in 36 cases (including 27 cases at age of less than 1 year). RSV and hMPV co-infection was common (n=22).
RSV is common pathogen of ARI in children from Suzhou. RSV viral activity peaks during winter and spring. The children at age of less than 1 year are susceptible to RSV. hMPV is also an important pathogen of ARI, with a peak detection rate between March and May. Mixed viral infection is common in children less than 1 year old.
调查中国苏州住院儿童急性呼吸道感染（ARI）的病毒病原体。
从1668例住院ARI儿童中获取鼻咽抽吸物样本。使用直接免疫荧光法检测常见呼吸道病毒，包括呼吸道合胞病毒（RSV）、甲型和乙型流感病毒、副流感病毒1、2和3以及腺病毒。通过RT-PCR检测人偏肺病毒（hMPV）基因片段。
597例（35.8%）检测到病毒病原体。RSV最为常见（17.6%）。RSV感染在1岁以下儿童中更为常见。RSV在冬季和春季的检出率最高。10.6%的病例检测到hMPV，3月至5月检出率最高。561例（33.6%）为单一病毒感染，36例为混合病毒感染（包括27例1岁以下儿童）。RSV和hMPV共感染常见（n = 22）。
RSV是苏州儿童ARI的常见病原体。RSV病毒活性在冬季和春季达到高峰。1岁以下儿童易感染RSV。hMPV也是ARI的重要病原体，3月至5月检出率最高。混合病毒感染在1岁以下儿童中常见。
