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[高能氦离子辐照后早期大鼠定向探索活动的急性消退]

[The acute extinction of orientational-exploratory activity in rats in the early periods after irradiation with high-energy helium ions].

作者信息

Savchenko N Ia

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1990 Nov-Dec;40(6):1169-74.

PMID:1965261
Abstract

Study of orienting-investigatory activity level, presence of grooming, manifestation of experimental neurosis, changes of rats motor activity after irradiation by helium ions in the beginning and at the end of the test at initial testing (using Dombrovskaia's maze) and also at repeated presentations with short time intervals, relation of latency and time of locomotor reaction revealed differences in the character of changes of correlation and intensity of nervous processes at different levels of doses: strengthening of inhibition processes at higher mid-lethal dose with a sharp increase of the CNS excitability and deficiency of internal inhibition process in the case of repeated presentations of the test.

摘要

研究定向探究活动水平、梳理行为的存在、实验性神经症的表现、在初始测试(使用东布罗夫斯卡娅迷宫)开始和结束时以及短时间间隔重复呈现时大鼠经氦离子照射后的运动活动变化、潜伏时间与运动反应时间的关系,发现在不同剂量水平下神经过程的相关性和强度变化特征存在差异:在较高的半致死剂量下抑制过程增强,中枢神经系统兴奋性急剧增加,且在测试重复呈现时内抑制过程不足。

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