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Wingspan 支架治疗急性缺血性脑卒中的组织病理学描述。

Histopathologic description of Wingspan stent in acute ischemic stroke.

机构信息

Department of Neurological Sciences, Rush University Medical Center, 1725 W. Harrison Street #1121, Chicago, IL 60612, USA.

出版信息

Neurocrit Care. 2009 Dec;11(3):377-80. doi: 10.1007/s12028-009-9258-0.

DOI:10.1007/s12028-009-9258-0
PMID:19655277
Abstract

OBJECTIVE AND IMPORTANCE

We report the histopathologic examination of Wingspan stent in acute ischemic stroke.

CLINICAL PRESENTATION

A 75-year-old female presented with acute left-hemiplegia due to right carotid terminus occlusion. Mechanical embolectomy was unsuccessful.

INTERVENTION

A Wingspan stent was placed from the distal intracranial carotid artery to the proximal middle cerebral artery stem and established partial antegrade flow. The patient died of malignant infarction on post-stroke day 7. At autopsy, embolized calcified atherosclerotic plaque fragments were noted within a non-occlusive thrombus over which the Wingspan stent was deployed. There was no evidence of intimal or media dissection or perforator ostium occlusion.

CONCLUSION

Our case provides a rare pathological description of intracranial stent placement in the setting of acute ischemic stroke.

摘要

目的和重要性

我们报告 Wingspan 支架在急性缺血性脑卒中中的组织病理学检查结果。

临床表现

一名 75 岁女性因右侧颈内动脉终末段闭塞导致急性左侧偏瘫。机械取栓术不成功。

介入治疗

从远端颈内动脉到近端大脑中动脉主干放置了 Wingspan 支架,建立了部分顺行血流。患者在卒中后第 7 天死于恶性梗死。尸检时,在 Wingspan 支架放置的非闭塞性血栓上发现了栓塞的钙化粥样硬化斑块碎片。没有内膜或中膜夹层或穿支口闭塞的证据。

结论

我们的病例提供了急性缺血性脑卒中时颅内支架置入的罕见病理描述。

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引用本文的文献

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Curr Cardiol Rep. 2010 Jan;12(1):14-9. doi: 10.1007/s11886-009-0069-x.

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Stroke. 2009 May;40(5):1910-2. doi: 10.1161/STROKEAHA.108.532416. Epub 2009 Jan 29.
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Self-expanding stents for recanalization of acute cerebrovascular occlusions.用于急性脑血管闭塞再通的自膨式支架
AJNR Am J Neuroradiol. 2007 May;28(5):816-22.
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Self-expanding versus balloon-mounted stents for vessel recanalization following embolic occlusion in the canine model: technical feasibility study.犬模型中栓塞性闭塞后血管再通的自膨式支架与球囊扩张式支架:技术可行性研究
AJNR Am J Neuroradiol. 2006 Nov-Dec;27(10):2069-72.
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Perforator stroke after elective stenting of symptomatic intracranial stenosis.症状性颅内狭窄择期支架置入术后的穿支动脉卒中
Neurology. 2006 Jun 27;66(12):1868-72. doi: 10.1212/01.wnl.0000219744.06992.bb.
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Perforator stroke following intracranial stenting: a sacrifice for the greater good?
Neurology. 2006 Jun 27;66(12):1803-4. doi: 10.1212/01.wnl.0000227198.02597.15.
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Multimodal reperfusion therapy for acute ischemic stroke: factors predicting vessel recanalization.急性缺血性卒中的多模式再灌注治疗:预测血管再通的因素
Stroke. 2006 Apr;37(4):986-90. doi: 10.1161/01.STR.0000209303.02474.27. Epub 2006 Mar 9.
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Intracranial angioplasty and stent placement for cerebral atherosclerosis.颅内血管成形术及支架置入术治疗脑动脉粥样硬化
J Vasc Interv Radiol. 2004 Jan;15(1 Pt 2):S123-32. doi: 10.1097/01.rvi.0000107488.61085.8f.
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Histopathological evaluation of middle cerebral artery after percutaneous intracranial transluminal angioplasty.
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