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医学毒理学与公共卫生——疾病控制与预防中心以及有毒物质与疾病登记署吸入性甲醇中毒研究及活动的最新情况。

Medical toxicology and public health--update on research and activities at the Centers for Disease Control and Prevention, and the Agency for Toxic Substances and Disease Registry inhalational methanol toxicity.

作者信息

Kleiman Richard, Nickle Richard, Schwartz Michael

机构信息

Office of Terrorism Preparedness and Emergency Response (OTPER), National Center for Environmental Health (NCEH), Office of the Director.

出版信息

J Med Toxicol. 2009 Sep;5(3):158-64. doi: 10.1007/BF03161229.

Abstract

Methanol toxicity is still a relatively common poisoning worldwide. Exposure typically occurs through ingestion, but there is potential for occupational inhalational exposures as well. People with potential exposure to methanol in any form need to wear the appropriate personal protective equipment, and they need to be familiar with proper detection methods. Medical professionals need to understand the metabolism of methanol and why knowledge of this metabolism is important for the diagnosis and management of this unique poison. Several methods of treatment exist for methanol toxicity. Through development of an under-standing of the pathophysiology behind the toxin, the appropriate measures can be taken.

摘要

甲醇中毒在全球范围内仍然是一种相对常见的中毒情况。接触通常通过摄入发生,但也存在职业性吸入接触的可能性。任何形式的潜在甲醇接触者都需要佩戴适当的个人防护装备,并且需要熟悉正确的检测方法。医学专业人员需要了解甲醇的代谢过程以及为何这种代谢知识对于诊断和处理这种独特毒物很重要。甲醇中毒有几种治疗方法。通过深入了解毒素背后的病理生理学,可以采取适当的措施。

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Uptake and disposition of inhaled methanol vapor in humans.人体对吸入甲醇蒸汽的摄取与处置
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Formate kinetics in methanol poisoning.甲醇中毒中的甲酸动力学
Hum Exp Toxicol. 2005 Feb;24(2):55-9. doi: 10.1191/0960327105ht503oa.

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