Dyduch A
Silesian Pediatric Center, Silesian School of Medicine, Zabrze, Poland.
Rom J Morphol Embryol. 1990 Jul-Dec;36(3-4):193-6.
Effects of dibutyryl cyclic AMP on enzymatic reaction for the thiamine pyrophosphatase, NADPH-tetrazolum, reductase, adenosine--triphosphatas -Ca-formol and acid phosphatase were investigated in the intestinal epithelium of the salivectomised mice. After intraperitoneal injections of dibutyryl cyclic AMP a marked increase of enzymatic reaction for thiamine pyrophosphatase (a marker of the Golgi complex) was noted, especially after 4 injections of dibutyryl cyclic AMP (twenty four hours after first injection). At the same time the intensities of reaction for the NADPH-r.t., ATP-ase-Ca-Formol and AcP did not undergo any changes in epithelial cells of intestinal villi after salivectomy and after dibutyrylo cyclic AMP administration. The obtained results suggest that dibutyrylo cyclic AMP probably regulates the Golgi complex activity.
在唾液腺切除小鼠的肠上皮中，研究了二丁酰环磷腺苷对硫胺素焦磷酸酶、NADPH - 四氮唑还原酶、腺苷三磷酸酶 - Ca - 甲酚和酸性磷酸酶酶促反应的影响。腹腔注射二丁酰环磷腺苷后，观察到硫胺素焦磷酸酶（高尔基体复合体的标志物）的酶促反应显著增加，尤其是在注射4次二丁酰环磷腺苷后（首次注射后24小时）。同时，在唾液腺切除后以及给予二丁酰环磷腺苷后，肠绒毛上皮细胞中NADPH - r.t.、ATP酶 - Ca - 甲酚和AcP的反应强度没有发生任何变化。所得结果表明，二丁酰环磷腺苷可能调节高尔基体复合体的活性。
