Silva C Y, Lenzy Y M, Goldberg L J
Department of Dermatology, Boston University School of Medicine, Boston, MA, USA.
J Cutan Pathol. 2010 May;37(5):597-9. doi: 10.1111/j.1600-0560.2009.01388.x. Epub 2009 Jul 28.
Temporal triangular alopecia (TTA) is a type of alopecia that is often congenital, and clinically exhibits hair loss on one or both temples. It is characterized histologically by a normal number of small hair follicles without significant inflammation. We report a patient with TTA whose biopsy exhibited a decreased number of hair follicles. There are limited reports of the histopathology of TTA, and most have utilized standard vertical sections. Of the handful of patients with transversely sectioned biopsies, follicular numbers have been reportedly normal. Our finding of a patient with TTA with a decreased number of hair follicles broadens the histologic spectrum of this disorder, and may have implications for pathogenesis.
颞部三角形脱发(TTA)是一种常为先天性的脱发类型,临床上表现为一侧或双侧颞部脱发。其组织学特征为小毛囊数量正常且无明显炎症。我们报告了一例TTA患者,其活检显示毛囊数量减少。关于TTA组织病理学的报道有限,且大多数采用标准垂直切片。在少数经横向切片活检的患者中,据报道毛囊数量正常。我们发现一例TTA患者毛囊数量减少,拓宽了该疾病的组织学谱,可能对发病机制有影响。