Department of Psychiatry and Psychotherapy, University Medical Center, Freiburg, Germany.
J Sleep Res. 2010 Mar;19(1 Pt 1):71-9. doi: 10.1111/j.1365-2869.2009.00742.x. Epub 2009 Jul 28.
Growing evidence indicates that sleep facilitates learning and memory processing. Sleep curtailment is increasingly common in adolescents. The aim of this study was to examine the effects of short-term sleep curtailment on declarative memory consolidation in adolescents. A randomized, cross-over study design was chosen. Twenty-two healthy subjects, aged 14-16 years, spent three consecutive nights in the sleep laboratory with a bedtime of 9 h during the first night (adaptation), 4 h during the second (partial sleep curtailment) and 9 h during the third night (recovery). The control condition consisted of three consecutive nights with bedtimes of 9 h. Both experimental conditions were separated by at least 3 weeks. The acquisition phase for the declarative tests was between 16:00 and 18:00 hours before the second night. Memory performance was examined in the morning after the recovery night. Executive function, attention and concentration were also assessed to control for any possible effects of tiredness. During the 4-h night, we observed a curtailment of 50% of non-rapid eye movement (non-REM), 5% of slow wave sleep (SWS) and 70% of REM sleep compared with the control night. Partial sleep curtailment of one night did not influence declarative memory retrieval significantly. Recall in the paired-associate word list task was correlated positively with percentage of non-REM sleep in the recovery night. Declarative memory consolidation does not appear to be influenced by short-term sleep curtailment in adolescents. This may be explained by the high ability of adolescents to compensate for acute sleep loss. The correlation between non-REM sleep and declarative memory performance supports earlier findings.
越来越多的证据表明，睡眠有助于学习和记忆处理。青少年中睡眠不足的情况越来越普遍。本研究旨在探讨短期睡眠剥夺对青少年陈述性记忆巩固的影响。采用随机交叉设计。选择 22 名健康受试者，年龄 14-16 岁，在睡眠实验室连续三晚，第一晚 9 小时（适应期），第二晚 4 小时（部分睡眠剥夺），第三晚 9 小时（恢复期）。对照组连续三晚 9 小时上床睡觉。两个实验条件至少相隔 3 周。陈述性测试的获得阶段在第二晚前 16:00 至 18:00 之间进行。在恢复夜后的早晨检查记忆表现。还评估了执行功能、注意力和注意力，以控制疲劳的任何可能影响。在 4 小时的夜间，我们观察到非快速眼动（非 REM）睡眠减少了 50%，慢波睡眠（SWS）减少了 5%，快速眼动（REM）睡眠减少了 70%，与对照组相比。一夜的部分睡眠剥夺对陈述性记忆检索没有明显影响。在配对联想单词列表任务中的回忆与恢复期非 REM 睡眠的百分比呈正相关。短期睡眠剥夺似乎不会影响青少年的陈述性记忆巩固。这可能是由于青少年有能力很好地补偿急性睡眠不足。非快速眼动睡眠与陈述性记忆表现之间的相关性支持了早期的发现。
