Taylor S D, Haldorson G J, Vaughan B, Pusterla N
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA, USA.
J Vet Intern Med. 2009 Sep-Oct;23(5):1097-102. doi: 10.1111/j.1939-1676.2009.0356.x. Epub 2009 Jul 28.
Gastric neoplasia of horses is incompletely described.
Provide history, clinical signs, and clinicopathological and pathological findings associated with gastric neoplasia in horses.
Twenty-four horses with gastric neoplasia.
Retrospective study. History, clinical signs, and clinicopathological and pathologic findings in horses diagnosed histologically with gastric neoplasia were reviewed.
Horses ranged in age from 9 to 25 years (median 18 years at presentation). There was no apparent breed or sex predisposition. The most common presenting complaints were inappetance (17/24), weight loss (14/24), lethargy (7/24), hypersalivation (7/24), colic (5/24), and fever (5/24). The most consistent clinical signs were tachypnea (10/19), decreased borborygmi (8/19), and low body weight (7/17). Useful diagnostic tests included rectal examination, routine blood analysis, gastroscopy, abdominocentesis, and transabdominal ultrasound examination. Anemia was the most common hematologic abnormality encountered (7/19), and hypercalcemia of malignancy was seen in 4/16 horses. Squamous cell carcinoma was the most common tumor identified (19/24), and was most often (14/19) found as a single ulcerated, necrotic mass in the nonglandular portion of the stomach. Other gastric neoplasms encountered were leiomyoma (n=2), mesothelioma (n=1), adenocarcinoma (n=1), and lymphoma (n=1). Metastatic neoplasia was found in 18/23 horses. The median time from onset of clinical signs to death was 4 weeks, and all horses died or were euthanized because of gastric neoplasia.
Squamous cell carcinoma is the most common primary gastric neoplasia in horses. The survival time after diagnosis of gastric neoplasia in horses is short.
马胃肿瘤的描述并不完整。
提供与马胃肿瘤相关的病史、临床症状以及临床病理和病理检查结果。
24匹患有胃肿瘤的马。
回顾性研究。对经组织学诊断为胃肿瘤的马的病史、临床症状以及临床病理和病理检查结果进行回顾。
马的年龄在9至25岁之间（就诊时中位数为18岁）。无明显品种或性别易感性。最常见的主诉是食欲不振（17/24）、体重减轻（14/24）、嗜睡（7/24）、流涎过多（7/24）、腹痛（5/24）和发热（5/24）。最一致的临床症状是呼吸急促（10/19）、肠蠕动音减弱（8/19）和体重低（7/17）。有用的诊断测试包括直肠检查、常规血液分析、胃镜检查、腹腔穿刺术和经腹超声检查。贫血是最常见的血液学异常（7/19），4/16匹马出现恶性肿瘤高钙血症。鳞状细胞癌是最常见的肿瘤（19/24），最常（14/19）在胃的非腺性部分发现为单个溃疡、坏死肿块。其他遇到的胃肿瘤有平滑肌瘤（n = 2）、间皮瘤（n = 1）、腺癌（n = 1）和淋巴瘤（n = 1）。18/23匹马发现有转移性肿瘤。从临床症状出现到死亡的中位时间为4周，所有马均因胃肿瘤死亡或实施安乐死。
鳞状细胞癌是马最常见的原发性胃肿瘤。马诊断胃肿瘤后的生存时间较短。
