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[2,5-二羟基苯磺酸盐的超氧化物歧化酶活性及光敏特性]

[Superoxide dismutase activity and photosensitizing properties of 2,5-dihydroxybenzolsulfonate].

作者信息

Lozovskaia E L, Kaplunskiĭ G D, Sapezhinskiĭ I I

出版信息

Biofizika. 1990 Nov-Dec;35(6):912-6.

PMID:1965686
Abstract

2,5-dihydroxybenzolsulphonate was shown to actively interact with the superoxide radical O2-. formed under UV-radiation of glycyltryptophan aqueous solutions or under visible light illumination of glycyltryptophan and riboflavine. The constant of the rate of reaction of 2,5-dihydroxybenzolsulphonate with O2-. was determined to be equal to 1.3 X 10(9) M-1s-1. A photosensitized effect of 2,5-dihydroxybenzolsulphonate under illumination with the light with 280 nm was found. The sensitization efficiency of glycyl-tryptophan oxidation increases when the experiments are carried out in the oxygen atmosphere.

摘要

2,5-二羟基苯磺酸盐被证明能与超氧阴离子O₂⁻ 发生积极相互作用。超氧阴离子O₂⁻ 是在甘氨酰色氨酸水溶液的紫外线辐射下或在甘氨酰色氨酸和核黄素的可见光照射下形成的。2,5-二羟基苯磺酸盐与O₂⁻ 的反应速率常数被测定为等于1.3×10⁹ M⁻¹s⁻¹。发现2,5-二羟基苯磺酸盐在280纳米光照射下具有光敏效应。当在氧气气氛中进行实验时,甘氨酰色氨酸氧化的敏化效率会提高。

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