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人类中循环单磷酸腺苷的血脑脊髓液屏障。

Blood-to-cerebrospinal fluid barrier for cyclic adenosine monophosphate in man.

作者信息

Brooks B R, Engel W K, Sode J

出版信息

Arch Neurol. 1977 Aug;34(8):468-9. doi: 10.1001/archneur.1977.00500200028004.

DOI:10.1001/archneur.1977.00500200028004
PMID:196581
Abstract

A definite blood to lumbar CSF barrier for cyclic adenosine monophosphate (cAMP) exists in man under physiologic conditions. Lumbar CSF cAMP level remained unchanged, while the CSF glucose level rose significantly after a glucagon hydrochloride infusion that caused a 40-fold increase in the plasma cAMP level.

摘要

在生理条件下,人体中存在明确的血液至腰段脑脊液的环磷酸腺苷(cAMP)屏障。静脉输注盐酸胰高血糖素使血浆cAMP水平升高40倍后,腰段脑脊液cAMP水平保持不变,而脑脊液葡萄糖水平显著升高。

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