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外源性3',5'-环磷酸腺苷在兔和猫体内的分布

Distribution of exogenous cyclic adenosine 3', 5'-monophosphate in rabbits and cats.

作者信息

Heikkinen E R

出版信息

Med Biol. 1977 Apr;55(2):82-7.

PMID:194115
Abstract

The appearance and disapperance of total radioactivity in plasma and cerebrospinal fluid (CSF) were studied after a single intravenous injection of tritium-labelled cyclic adenosine 3', 5'-monophosphate (cAMP) into rabbits and cats. The radioactivity was rapidly cleared both from plasma and relatively stable when compared to plasma cAMP level. Exogenous cAMP in plasma does not seen to distribute into CSF by a simple diffusion.

摘要

在给兔子和猫单次静脉注射氚标记的环磷酸腺苷（cAMP）后，研究了血浆和脑脊液（CSF）中总放射性的出现和消失情况。与血浆cAMP水平相比，放射性从血浆中迅速清除且相对稳定。血浆中的外源性cAMP似乎不是通过简单扩散进入脑脊液的。

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