Education and Research Center for Marine Resources and Environment, Faculty of Fisheries, Kagoshima University, 50-20 Shimoarata 4-Chome, Kagoshima 890-0056, Japan.
Environ Toxicol. 2011 Feb;26(1):29-36. doi: 10.1002/tox.20526.
Interspecies differences in the accumulation of dietary tributyltin (TBT) between sea perch, Lateolabrax japonicus, and red sea bream, Pagrus major, were studied. Although TBTs in both species reached steady-state condition in low-concentration group (L-group, 200 ng/g nominal concentration) by 1 week, it increased up to the end of exposure in high-concentration group (H-group, 3000 ng/g nominal concentration). In H-group, the accumulation rate of TBT in sea perch from 1 to 2 weeks was much higher than in red sea bream, which were 2.4-fold for sea perch and 1.7-fold for red sea bream, although TBT concentrations were similar between sea perch and red sea bream in L-group. Furthermore, in the H-group, the concentrations of TBT at 1 and 2 weeks were about 1.3- and 1.9-fold, respectively, higher in the sea perch than in the red sea bream. On the other hand, DBT residue in red sea bream was about 1.4-fold higher in sea perch for the L-group but concentrations were similar in both fishes for the H-group. These results suggest that red sea bream could metabolize faster the TBT to DBT than sea perch. This study also reveals that fish probably could absorb TBT through the food chain. The uptake of TBT by fish should be regarded in the real environment, because TBT concentration in seawater has been decreasing and now already at significantly low level.
研究了鲈鱼（Lateolabrax japonicus）和真鲷（Pagrus major）对膳食三丁基锡（TBT）的积累的种间差异。尽管在低浓度组（L 组，名义浓度 200ng/g）中，两种鱼在 1 周内达到了稳定状态，但在高浓度组（H 组，名义浓度 3000ng/g）中，TBT 浓度一直增加到暴露结束。在 H 组中，鲈鱼从第 1 周到第 2 周的 TBT 积累率远高于真鲷，分别为鲈鱼的 2.4 倍和真鲷的 1.7 倍，尽管在 L 组中，鲈鱼和真鲷的 TBT 浓度相似。此外，在 H 组中，第 1 周和第 2 周的 TBT 浓度分别比真鲷高约 1.3 倍和 1.9 倍。另一方面，在 L 组中，DBT 残留在真鲷中的含量比鲈鱼高约 1.4 倍，但在 H 组中，两种鱼的浓度相似。这些结果表明，真鲷可能比鲈鱼更快地将 TBT 代谢为 DBT。本研究还表明，鱼类可能通过食物链吸收 TBT。在真实环境中，应该考虑鱼类对 TBT 的摄取，因为海水中的 TBT 浓度一直在下降，现在已经处于明显的低水平。
