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血流中的混沌平流。

Chaotic advection in blood flow.

作者信息

Schelin A B, Károlyi Gy, de Moura A P S, Booth N A, Grebogi C

机构信息

Instituto de Física, Universidade de São Paulo, Caixa Postal 66318, São Paulo 05315-970, SP, Brazil.

出版信息

Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Jul;80(1 Pt 2):016213. doi: 10.1103/PhysRevE.80.016213. Epub 2009 Jul 29.

DOI:10.1103/PhysRevE.80.016213
PMID:19658798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3657681/
Abstract

In this paper we argue that the effects of irregular chaotic motion of particles transported by blood can play a major role in the development of serious circulatory diseases. Vessel wall irregularities modify the flow field, changing in a nontrivial way the transport and activation of biochemically active particles. We argue that blood particle transport is often chaotic in realistic physiological conditions. We also argue that this chaotic behavior of the flow has crucial consequences for the dynamics of important processes in the blood, such as the activation of platelets which are involved in the thrombus formation.

摘要

在本文中,我们认为血液运输的粒子不规则混沌运动的影响在严重循环系统疾病的发展中可能起主要作用。血管壁不规则会改变流场,以一种复杂的方式改变生物化学活性粒子的运输和激活。我们认为在现实生理条件下,血液粒子运输通常是混沌的。我们还认为这种流动的混沌行为对血液中重要过程的动力学有至关重要的影响,比如参与血栓形成的血小板的激活。

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本文引用的文献

1
The impact of blood rheology on the molecular and cellular events underlying arterial thrombosis.血液流变学对动脉血栓形成潜在分子和细胞事件的影响。
J Mol Med (Berl). 2006 Dec;84(12):989-95. doi: 10.1007/s00109-006-0101-1. Epub 2006 Sep 30.
2
Spatial models of prebiotic evolution: soup before pizza?益生元进化的空间模型:先有汤还是先有披萨?
Orig Life Evol Biosph. 2003 Oct;33(4-5):319-55. doi: 10.1023/a:1025742505324.
3
Hemodynamic analysis of an adult vein of Galen aneurysm malformation by use of 3D image-based computational fluid dynamics.使用基于3D图像的计算流体动力学对成人Galen静脉瘤样畸形进行血流动力学分析。
AJNR Am J Neuroradiol. 2003 Jun-Jul;24(6):1075-82.
4
Small-scale structure of nonlinearly interacting species advected by chaotic flows.
Chaos. 2002 Jun;12(2):470-480. doi: 10.1063/1.1468248.
5
Introduction: Active chaotic flow.
Chaos. 2002 Jun;12(2):372. doi: 10.1063/1.1482195.
6
Competing populations in flows with chaotic mixing.
Theor Popul Biol. 2003 Mar;63(2):77-90. doi: 10.1016/s0040-5809(02)00035-7.
7
Aspects of hydrodynamic shear regulating shear-induced platelet activation and self-association of von Willebrand factor in suspension.流体动力剪切在悬浮液中调节剪切诱导的血小板活化和血管性血友病因子自缔合的相关方面。
Blood. 2003 Apr 1;101(7):2637-45. doi: 10.1182/blood-2002-05-1550. Epub 2002 Nov 27.
8
Platelets in atherothrombosis.动脉粥样硬化血栓形成中的血小板。
Nat Med. 2002 Nov;8(11):1227-34. doi: 10.1038/nm1102-1227.
9
Mesoscale vortices and the paradox of the plankton.中尺度涡旋与浮游生物悖论
Proc Biol Sci. 2000 Sep 7;267(1454):1795-800. doi: 10.1098/rspb.2000.1212.
10
Residence times and basins of attraction for a realistic right internal carotid artery with two aneurysms.具有两个动脉瘤的实际右侧颈内动脉的停留时间和吸引域
Biorheology. 2002;39(3-4):387-93.