Shadden Shawn C, Arzani Amirhossein
Department of Mechanical Engineering, University of California, 5126 Etcheverry Hall, Berkeley, CA , 94720-1740, USA,
Ann Biomed Eng. 2015 Jan;43(1):41-58. doi: 10.1007/s10439-014-1070-0. Epub 2014 Jul 25.
Recent advances in imaging, modeling, and computing have rapidly expanded our capabilities to model hemodynamics in the large vessels (heart, arteries, and veins). This data encodes a wealth of information that is often under-utilized. Modeling (and measuring) blood flow in the large vessels typically amounts to solving for the time-varying velocity field in a region of interest. Flow in the heart and larger arteries is often complex, and velocity field data provides a starting point for investigating the hemodynamics. This data can be used to perform Lagrangian particle tracking, and other Lagrangian-based postprocessing. As described herein, Lagrangian methods are necessary to understand inherently transient hemodynamic conditions from the fluid mechanics perspective, and to properly understand the biomechanical factors that lead to acute and gradual changes of vascular function and health. The goal of the present paper is to review Lagrangian methods that have been used in post-processing velocity data of cardiovascular flows.
成像、建模和计算方面的最新进展迅速扩展了我们对大血管(心脏、动脉和静脉)血流动力学进行建模的能力。这些数据编码了大量常常未得到充分利用的信息。对大血管中的血流进行建模(以及测量)通常相当于求解感兴趣区域内随时间变化的速度场。心脏和较大动脉中的血流通常很复杂,速度场数据为研究血流动力学提供了一个起点。该数据可用于进行拉格朗日粒子追踪以及其他基于拉格朗日的后处理。如本文所述,从流体力学角度理解固有瞬态血流动力学状况以及正确理解导致血管功能和健康发生急性和渐进性变化的生物力学因素,拉格朗日方法是必不可少的。本文的目的是综述已用于心血管血流速度数据后处理的拉格朗日方法。