透析器膜诱导白三烯B4生成
Induction of leukotriene B4 formation by dialyzer membranes.
作者信息
Schiffl H, Strasser T
机构信息
Medizinische Klinik Innenstadt, Universität München, FRG.
出版信息
Biomater Artif Cells Artif Organs. 1990;18(5):585-90. doi: 10.3109/10731199009117325.
PMID:1965950
Abstract
Interactions between blood and dialysis membranes lead to activation of the 5-lipoxygenase pathway of the arachiodonic acid metabolism during hemodialysis. Newly generated leukotriene B4 (LTB4) may contribute to the multifaceted granulocyte abnormalities of uremic patients.
摘要
血液与透析膜之间的相互作用会导致血液透析期间花生四烯酸代谢的5-脂氧合酶途径被激活。新生成的白三烯B4（LTB4）可能导致尿毒症患者出现多方面的粒细胞异常。
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