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[促肾上腺皮质激素治疗诱导的主动脉瓣下梗阻相关的心脏肥大]

[Cardiac hypertrophy associated with subaortic obstruction induced by adrenocorticotropic hormone treatment].

作者信息

Martí V, Guasch E, Binia M, Subirana M T

机构信息

Departamento de Cardiología, Hospital de la Santa Creu i Sant Pau, Barcelona.

出版信息

Rev Esp Cardiol. 1990 Nov;43(9):652-4.

PMID:1965992
Abstract

A 7 months-old child affected of West syndrome presented a cardiac hypertrophy with subaortic obstruction induced by adrenocorticotropic hormone treatment. The administration of this hormone may induce a Cushing syndrome; at high doses has chronotropic and inotropic positive effects and may produce arterial hypertension and cardiac hypertrophy. We pointed out the importance of the echocardiography-Doppler in the diagnosis and follow-up of the cardiac hypertrophy with subaortic obstruction as well as the reversibility of the cardiac involvement when the drug is suppressed.

摘要

一名患有韦斯特综合征的7个月大儿童在接受促肾上腺皮质激素治疗后出现心脏肥大并伴有主动脉下梗阻。这种激素的使用可能会诱发库欣综合征;高剂量时具有变时性和变力性的正性作用,可能会导致动脉高血压和心脏肥大。我们指出了超声心动图 - 多普勒检查在诊断和随访主动脉下梗阻性心脏肥大中的重要性,以及停用该药物后心脏受累的可逆性。

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