Cardiovascular Clinic, Bad Neustadt, Germany.
J Thorac Cardiovasc Surg. 2010 Jan;139(1):98-102. doi: 10.1016/j.jtcvs.2009.03.058. Epub 2009 Jun 10.
The aim of this study was to evaluate the clinical and echocardiographic results after aortic valve reconstruction with a novel surgical technique consisting of basal cusp enlargement with an autologous pericardial patch.
Between December 2005 and June 2008, a total of 106 consecutive patients underwent elective valve-sparing aortic root repair at Cardiovascular Clinic, Bad Neustadt, Germany. Fifty-nine patients required additional procedures on the aortic cusps; among them, in 10 cases basal cusp enlargement was used for restoration of coaptation area. All these patients had an ascending aortic aneurysm combined with aortic insufficiency, which was severe (4+) in 2 cases and moderate to severe (3+) in 4. The root repair was performed with valve reimplantation (David technique) in 1 case and the author's own single-patch technique in the other 9. Partial and total arch replacements were performed in 3 and 1 cases, respectively.
The postoperative echocardiography at discharge showed no aortic regurgitation in 7 cases and trivial regurgitation in 3. The average coaptation height of the leaflets was 9.9 + or - 0.6 mm, and the mean gradient across the valve was 5.4 + or - 1.9 mm Hg. At follow-up as late as 31 months, all patients were alive with echocardiographic findings unchanged from the early postoperative examinations.
The technique presented here allows an individualized reconstruction of the aortic cusps, leading to considerable improvement in coaptation area, in patients who have aortic leaflet prolapse or restriction caused by complex aortic root and valve disease.
本研究旨在评估一种新的外科技术(即使用自体心包补片扩大瓣叶基底部)进行主动脉瓣重建后的临床和超声心动图结果。
2005 年 12 月至 2008 年 6 月期间,德国巴特诺伊施塔特心血管诊所共对 106 例连续患者进行了择期保留主动脉瓣根部修复手术。59 例患者需对主动脉瓣瓣叶进行附加手术;其中,10 例采用扩大瓣叶基底部来修复瓣叶对合区。所有这些患者均合并升主动脉瘤和主动脉瓣关闭不全,其中 2 例为重度(4+),4 例为中重度至重度(3+)。根部修复术在 1 例中采用了瓣膜再植入(David 技术),在其余 9 例中采用了作者自创的单补丁技术。3 例和 1 例分别进行了部分和全弓置换。
出院时的术后超声心动图显示,7 例无主动脉瓣反流,3 例为轻微反流。瓣叶对合高度平均为 9.9±0.6mm,瓣口平均跨瓣压差为 5.4±1.9mmHg。在随访时间长达 31 个月时,所有患者均存活,且超声心动图结果与早期术后检查相比无变化。
对于因复杂主动脉根部和瓣叶病变而导致主动脉瓣叶脱垂或瓣叶受限的患者,本研究中介绍的技术可实现个体化的主动脉瓣瓣叶重建,显著改善瓣叶对合区。