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肺气肿肺移植的最新进展。

Update on lung transplantation for emphysema.

作者信息

Denlinger Chadrick E, Meyers Bryan F

机构信息

Department of Surgery, Washington University School of Medicine, 3108, Queeny Tower, One Barnes-Jewish Hospital Plaza, St. Louis, MO 63110-1013, USA.

出版信息

Thorac Surg Clin. 2009 May;19(2):275-83. doi: 10.1016/j.thorsurg.2009.03.001.

Abstract

Lung transplantation in the modern era remains an evolving field and a viable option for patients suffering from end-stage emphysema. Recent modifications for recipient prioritization has resulted in a modest decrease in the number of patients with emphysema receiving transplants. More time will be required to determine what impact, if any, these modifications will have on the overall survival of patients with end-stage emphysema. Ongoing research will address persistent issues with lung transplantation, most notably, primary graft dysfunction and chronic BOS.

摘要

现代肺移植仍是一个不断发展的领域,对于终末期肺气肿患者来说是一种可行的选择。近期对受者优先排序的调整导致接受移植的肺气肿患者数量略有下降。需要更多时间来确定这些调整对终末期肺气肿患者的总体生存率是否有影响以及有何种影响。正在进行的研究将解决肺移植中持续存在的问题,最显著的是原发性移植物功能障碍和慢性细支气管闭塞综合征。

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