Pain D, Murakami H, Schnell D J, Blobel G
Laboratory of Cell Biology, Howard Hughes Medical Institute, Rockefeller University, New York 10021.
Indian J Biochem Biophys. 1990 Dec;27(6):443-5.
An anti-idiotypic antibody approach was used to identify chloroplast and mitochondrial protein component(s) which interact with the corresponding signal sequence. The proteins thus identified can be operationally defined as receptor(s) for import of proteins into chloroplasts and mitochondria. The import receptor(s) was found in "contact sites" between the outer and inner membrane of chloroplast envelope or of mitochondria.
采用抗独特型抗体方法来鉴定与相应信号序列相互作用的叶绿体和线粒体蛋白质成分。如此鉴定出的蛋白质在操作上可定义为蛋白质导入叶绿体和线粒体的受体。发现该导入受体存在于叶绿体被膜或线粒体的外膜与内膜之间的“接触位点”。
