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急性尿潴留和前列腺特异性抗原水平升高患者的经尿道前列腺切除术与前列腺穿刺活检同步进行。

Simultaneous transurethral resection of prostate and prostate needle biopsy in patients with acute urinary retention and elevated prostate specific antigen levels.

作者信息

Chen Yen-Ta, Chiang Po-Hui, Hsu Chun-Chien

机构信息

Department of Urology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.

出版信息

Chang Gung Med J. 2009 Jul-Aug;32(4):417-22.

Abstract

BACKGROUND

To evaluate the safety and accuracy of simultaneous transrectal ultrasonography (TRUS)-guided prostate biopsy and transurethral resection of prostate (TURP), patients with acute urinary retention (AUR) who underwent simultaneous prostate biopsy and TURP were compared with those treated by TURP alone.

METHODS

From July 2000 to Jun 2004, 21 patients older than 70 years with AUR were included in each group. Patients with elevated prostate specific antigen (PSA) levels > 4 ng(/ml) underwent TURP and TRUS-guided biopsy simultaneously (group I), while those with normal PSA levels < 4 ng(/ml) received TURP alone (group II). The average ages of group I and group II patients were 72.4 and 72.5 years.

RESULTS

In group I, 4 patients (19%) were diagnosed with prostate cancer; 2 had metastasis and received hormone therapy; and 1 had localized cancer and was treated with brachytherapy. An 82-year-old patient with localized cancer opted for watchful waiting. Compared to group II, patients in group I did notshow aggregated morbidity, such as prolonged hospital stay, hematuria, or fever.

CONCLUSION

Simultaneous TURP and TRUS-guided biopsy in healthy AUR patients does not increase the risk of morbidity. Furthermore, with this approach patients can recover from the stress of AUR and have a definite diagnosis of their condition.

摘要

背景

为评估经直肠超声(TRUS)引导下前列腺穿刺活检与经尿道前列腺切除术(TURP)同时进行的安全性和准确性,将接受前列腺穿刺活检与TURP同时进行的急性尿潴留(AUR)患者与仅接受TURP治疗的患者进行比较。

方法

2000年7月至2004年6月,每组纳入21例年龄大于70岁的AUR患者。前列腺特异性抗原(PSA)水平>4 ng(/ml)的患者同时接受TURP和TRUS引导下的活检(I组),而PSA水平<4 ng(/ml)的患者仅接受TURP(II组)。I组和II组患者的平均年龄分别为72.4岁和72.5岁。

结果

I组中,4例(19%)患者被诊断为前列腺癌;2例有转移并接受了激素治疗;1例为局限性癌症并接受了近距离放射治疗。一名82岁局限性癌症患者选择了观察等待。与II组相比,I组患者未出现诸如住院时间延长、血尿或发热等合并症聚集情况。

结论

健康的AUR患者同时进行TURP和TRUS引导下的活检不会增加发病风险。此外,通过这种方法,患者可以从AUR的应激中恢复,并对其病情有明确诊断。

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