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在预防医学中使用自动血压装置检测外周动脉疾病时踝臂指数的准确性。

Accuracy of ankle-brachial index using an automatic blood pressure device to detect peripheral artery disease in preventive medicine.

作者信息

Benchimol Daniel, Pillois Xavier, Benchimol Alain, Houitte André, Sagardiluz Pierre, Tortelier Luc, Bonnet Jacques

机构信息

Inserm U828, université Victor-Segalen de Bordeaux 2, hôpital Cardiologique, avenue du Haut-Lévêque, 33604 Pessac, France.

出版信息

Arch Cardiovasc Dis. 2009 Jun-Jul;102(6-7):519-24. doi: 10.1016/j.acvd.2009.03.011. Epub 2009 Jun 21.

Abstract

BACKGROUND

Previously, we validated determination of ankle-brachial index using an automatic blood pressure device.

AIM

To test the feasibility and accuracy of the automatic method in assessing pathological ankle-brachial indexes in routine preventive examinations.

METHODS

Two physicians enrolled 354 subjects (74% men) randomly for automatic ankle-brachial index measurements using an OMRON HM 722 device. Ankle-brachial index was calculated by dividing the highest value obtained at each ankle by the highest arm value. Each subject with an abnormal (less than 0.90) automatic index and the six subsequent subjects underwent Doppler index determination.

RESULTS

Automatic ankle-brachial index determination was possible in both ankles in 350 subjects (99%; mean time 8.1+/-2.1 minutes). The incidence of abnormal automatic ankle-brachial index was 8% (n=28). Correlations between the automatic and Doppler methods were good in left and right legs (r=0.84 and 0.78, respectively; p<0.001). In subjects with an abnormal automatic index, correlations with Doppler indexes were good in both legs (r=0.67, p<0.001). In terms of detecting an abnormal index in a routine preventive examination, the automatic method had good sensitivity (92%), specificity (98%), positive predictive value (86%), negative predictive value (99%) and accuracy (97% compared with the Doppler method). Good results were obtained in subjects with an abnormal index in terms of agreement and concordance with the Doppler method (kappa=0.87).

CONCLUSIONS

The use of a commercially available automatic blood pressure device to detect peripheral artery disease appears feasible and quick in routine medical examinations.

摘要

背景

此前,我们已验证了使用自动血压装置测定踝臂指数的方法。

目的

测试该自动方法在常规预防性检查中评估病理性踝臂指数的可行性和准确性。

方法

两名医生随机招募了354名受试者(74%为男性),使用欧姆龙HM 722装置自动测量踝臂指数。踝臂指数通过将每个脚踝获得的最高值除以最高手臂值来计算。每个自动指数异常(低于0.90)的受试者以及随后的六名受试者接受多普勒指数测定。

结果

350名受试者(99%)的双踝均可进行自动踝臂指数测定(平均时间8.1±2.1分钟)。自动踝臂指数异常的发生率为8%(n = 28)。自动测量法与多普勒测量法在左腿和右腿的相关性良好(r分别为0.84和0.78;p<0.001)。在自动指数异常的受试者中,双腿与多普勒指数的相关性均良好(r = 0.67,p<0.001)。在常规预防性检查中检测异常指数方面,自动测量法具有良好的敏感性(92%)、特异性(98%)、阳性预测值(86%)、阴性预测值(99%)和准确性(与多普勒测量法相比为97%)。在指数异常的受试者中,与多普勒测量法在一致性和符合度方面取得了良好结果(kappa = 0.87)。

结论

在常规医学检查中,使用市售自动血压装置检测外周动脉疾病似乎可行且快速。

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