Kawamura Takao
Cardioclínica Araçatuba, Araçatuba, SP - Brasil.
Arq Bras Cardiol. 2008 May;90(5):294-8. doi: 10.1590/s0066-782x2008000500003.
Assessing Ankle-Brachial Index is an essential procedure in clinical settings, but since its measurement by the gold standard Doppler Ultrasonic (DU) technique is impaired by technical difficulties, it is underperformed.
The aim of this study was to assess the efficacy of an automated oscillometric device (AOD) by performing Ankle-Brachial Index (ABI) assessments and to suggest delta brachial-brachial (delta-BB) and delta-ABI as markers of cardiovascular risk.
In this observational and descriptive study, 247 patients (56.2% females, mean age 62.0 years) had their arterial blood pressure (ABP) measured for ABI calculation. Two AOD (OMRON-HEM705CP) devices were used for simultaneous measurements of the ABP, first of the two arms and then of the arm with higher systolic ABP and a leg, first the left and then the right one. When leg ABP measurements were not possible, ABI determination was performed by using the standard Doppler Ultrasonic (DU) technique. Patients were designated to Group N (normal ABI: 0.91 to 1.30) or Group A (abnormal ABI: < or =0.90 or >1.30). Other indexes were also calculated: delta-BB (absolute difference in mmHg of systolic ABP between arms) and delta-ABI (absolute difference of ABI between legs) and the results were compared.
In most patients (90.7%), it was possible to determine the ABI. Group N data allowed calculation of the 95th percentile reference values (RV) of delta-BB (0 to 8 mmHg) and delta-ABI (0 to 0.13). When compared to Group N, Group A had a significantly higher prevalence of high values greater than the RVs of delta-ABI (30 of 52 and 10 of 195, respectively; Odds Ratio = 25.23; p<0.0001) and delta-BB (13 of 52 and 7 of 195, respectively; Odds Ratio = 8.95; p<0.0001).
In most patients, the ABI could be measured by AOD. Both indexes, delta-BB and delta-ABI greater than the RVs, were significantly more prevalent in patients with abnormal ABI values, and their usefulness as new markers of cardiovascular disease should be further appraised in epidemiological studies.
评估踝臂指数是临床中的一项重要检查,但由于采用金标准多普勒超声(DU)技术测量时存在技术困难,该检查的实施情况并不理想。
本研究旨在通过进行踝臂指数(ABI)评估来评估自动振荡式设备(AOD)的有效性,并提出肱动脉压差(delta-BB)和踝臂指数差值(delta-ABI)作为心血管风险标志物。
在这项观察性描述性研究中,对247例患者(女性占56.2%,平均年龄62.0岁)测量动脉血压(ABP)以计算ABI。使用两台AOD(欧姆龙HEM705CP)设备同时测量ABP,先测量双臂,然后测量收缩压较高的手臂和一条腿的血压,先测左腿,再测右腿。当无法测量腿部ABP时,采用标准多普勒超声(DU)技术测定ABI。将患者分为N组(正常ABI:0.91至1.30)或A组(异常ABI:≤0.90或>1.30)。还计算了其他指标:delta-BB(双臂收缩压ABP的毫米汞柱绝对差值)和delta-ABI(双腿ABI的绝对差值),并对结果进行比较。
大多数患者(90.7%)能够测定ABI。N组数据可计算出delta-BB(0至8毫米汞柱)和delta-ABI(0至0.13)的第95百分位数参考值(RV)。与N组相比,A组中高于delta-ABI参考值的高值患病率显著更高(分别为52例中的30例和195例中的10例;优势比=25.23;p<0.0001),delta-BB也是如此(分别为52例中的13例和195例中的7例;优势比=8.95;p<0.0001)。
大多数患者的ABI可用AOD测量。delta-BB和delta-ABI这两个指标高于参考值在ABI值异常的患者中显著更为常见,其作为心血管疾病新标志物的实用性应在流行病学研究中进一步评估。