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大脑中的CD95/Fas——不仅仅是一种杀手分子。

CD95/Fas in the brain--not just a killer.

作者信息

Beier Christoph P, Schulz Jörg B

机构信息

Department of Neurology, University Hospital RWTH Aachen, Aachen, Germany.

出版信息

Cell Stem Cell. 2009 Aug 7;5(2):128-30. doi: 10.1016/j.stem.2009.07.008.

Abstract

Although CD95 (Fas/Apo-1) has long been known to be broadly expressed in the brain, its function has remained enigmatic. In this issue of Cell Stem Cell, Corsini et al. (2009) now show that CD95 serves as a potent activator of neurogenesis in both the healthy and injured brain.

摘要

尽管长期以来人们都知道CD95(Fas/Apo-1)在大脑中广泛表达,但其功能一直成谜。在本期的《细胞·干细胞》杂志中,科尔西尼等人(2009年)现在表明,CD95在健康大脑和受损大脑中都是神经发生的有力激活剂。

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