Ciubotaru M
Medico-Pharmaceutical Institute, Chair of Endocrinology, Bucharest, Romania.
Endocrinologie. 1990 Jul-Dec;28(3-4):159-69.
From the beginning I want to explain some interesting notions about cytodifferentiation, these being seen, in my view, like an Instructive Informatory Theory. Then, I tried to present the sustaining arguments for an extracellular differentiation. These arguments reveal that final decision in differentiation process are the receptor molecules. Therefore, I present some actual questions arisen about the correlations between receptors and secondary messengers. The hormones action models are the single way to clear up the vagueness about the nucleus-receptor connection.
从一开始我就想解释一些关于细胞分化的有趣概念，在我看来，这些概念可被视为一种指导性信息理论。然后，我试图阐述支持细胞外分化的论据。这些论据表明，分化过程中的最终决定因素是受体分子。因此，我提出了一些关于受体与第二信使之间相关性的实际问题。激素作用模型是消除细胞核与受体联系方面模糊性的唯一途径。
