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激素——细胞分化过程新认识的模型。第一部分。分化——单个细胞的选择?

The hormones--a model for a new understanding of cell differentiation process. Part I. Differentiation--an individual cell option?

作者信息

Ciubotaru M

机构信息

Medico-Pharmaceutical Institute, Chair of Endocrinology, Bucharest, Romania.

出版信息

Endocrinologie. 1990 Jul-Dec;28(3-4):159-69.

PMID:1966536
Abstract

From the beginning I want to explain some interesting notions about cytodifferentiation, these being seen, in my view, like an Instructive Informatory Theory. Then, I tried to present the sustaining arguments for an extracellular differentiation. These arguments reveal that final decision in differentiation process are the receptor molecules. Therefore, I present some actual questions arisen about the correlations between receptors and secondary messengers. The hormones action models are the single way to clear up the vagueness about the nucleus-receptor connection.

摘要

从一开始我就想解释一些关于细胞分化的有趣概念,在我看来,这些概念可被视为一种指导性信息理论。然后,我试图阐述支持细胞外分化的论据。这些论据表明,分化过程中的最终决定因素是受体分子。因此,我提出了一些关于受体与第二信使之间相关性的实际问题。激素作用模型是消除细胞核与受体联系方面模糊性的唯一途径。

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