Tsunoda T, Segawa T, Eto T, Izawa K, Tsuchiya R
Second Department of Surgery, Nagasaki University School of Medicine, Japan.
J Gastroenterol Hepatol. 1990 Nov-Dec;5(6):595-600. doi: 10.1111/j.1440-1746.1990.tb01112.x.
Sixteen long-term (more than 5 years) survivors after hepatic resection performed for hepatocellular carcinoma (HCC) from 1970 to 1988, were reviewed. The mean age of the patients was 51 years. There were 11 males and 5 females. HBs antigen was positive in 9 patients. Liver cirrhosis was associated with 11 patients but its severity was designated as Child's A in all patients except one. The mean tumour diameter was 2.8 cm and was relatively small. At the first operation, limited procedures (i.e. partial hepatectomy and subsegmentectomy) were employed in 87.5% of patients. A large percentage of tumours were located in S5 and S6 segments. A recurrence of HCC occurred in 9 patients after the first resection. A second resection was carried out in 7 patients, in 2 of which a third resection was done. Transcatheter arterial embolization (TAE) was performed on 4 patients. These results show that, in addition to detection of small tumours and early resection, repeated operation or TAE for treatment of recurrent HCC was important in achieving long-term survival after HCC resection.
对1970年至1988年期间因肝细胞癌（HCC）接受肝切除术后存活16例长期（超过5年）的患者进行了回顾性研究。患者的平均年龄为51岁。男性11例，女性5例。9例患者乙肝表面抗原呈阳性。11例患者伴有肝硬化，但除1例患者外，所有患者的肝硬化严重程度均为Child A级。肿瘤平均直径为2.8 cm，相对较小。首次手术时，87.5%的患者采用了有限手术（即肝部分切除术和肝段下切除术）。大部分肿瘤位于S5和S6段。9例患者首次切除术后发生HCC复发。7例患者进行了二次切除，其中2例进行了三次切除。4例患者接受了经导管动脉栓塞术（TAE）。这些结果表明，除了发现小肿瘤和早期切除外，对复发性HCC进行重复手术或TAE治疗对于HCC切除术后实现长期生存很重要。
